Stat 6573 Statistical genetics
This is a basic applied course of statistics addressing study designs, ascertainment bias, confounding and other statistical issues in genetics. It covers a range of topics that include population genetics principles, segregation analysis, pedigree analysis, association and linkage disequilibrium, candidate gene and candidate region studies, GAWs, and rare-variant analysis.
Undergraduate statistics inference and regression courses. Previous exposure to genetics and biology desirable.
- K Lange, 2003. Mathematical and statistical methods for genetic analysis.
- EA Thompson, 2000. Statistical inference from genetic data on pedigrees.
Institute of Mathematical Statistics.
- DC Thomas, 2004. Statistical methods in genetic epidemiology. Oxford.
- M Lynch and B Walsh. 1998. Genetic analysis of quantitative traits. Sinauer.
- JD Terwilliger and J Ott, 1994. Handbook of human genetic linkage. Johns
- BS Weir, 1996. Genetic data analysis II. Sinauer.