Mitchell Browne

Mahzad

  • M.Sc. Candidate
  • Research: My research employs the use of a Hidden Markov model to detect antimicrobial peptide motifs from translated nucleotide sequences obtained from the Atlantic cod Genomics project. Primers for antimicrobial peptide coding nucleotide sequences were designed, and the full-length cDNA sequences of these were obtained by 5' and 3' RACE (Rapid Amplification of cDNA Ends) and subsequent sequencing upon vector ligation. Quantitative reverse transcription polymerase chain reaction (QPCR) is then used to examine the expression profile of these genes. The peptides will then be chemically synthesized, purified, and tested for activity by antimicrobial assay. Finally, these peptides will be characterized by circular dichroism and NMR.'
  • Co-supervised by Dr. Matthew Rise (OSC, Canada Research Chair in Marine Biotechnology)
  • Academic Background: B.Sc. (Honours), Biochemistry

Contact

Valerie Booth

230 Elizabeth Ave, St. John's, NL, CANADA, A1B 3X9

Postal Address: P.O. Box 4200, St. John's, NL, CANADA, A1C 5S7

Tel: (709) 864-8000