Faculty Research

2010 - 2011

Completed

Dawson LM, Power P, Fontaine D. Cervical Cancer Screening in Newfoundland and Labrador - Abstract and oral presentation Gynecologic Oncologists Canada ACM 2010.

Greenslade V, Barry I, Fitzgerald K, Dawson LM. Barriers to Cervical Screening in Newfoundland and Labrador - Presented International Association of Cancer Nurses, 2010.

Crane JMG, White J, Murphy P, Burrage L, Hutchens D. The Effect of Gestational Weight Gain in Obese Women on Obstetric and Neonatal Outcomes - Presented American College of Obstetricians and Gynecologists, Annual Clinical Meeting, 2010.

Bartellas E, Crane J. Case Report: Self Inflicted Sudden Fetal Death - Presented Discipline Obstetrics and Gynecology, Memorial University of Newfoundland, Annual Resident Research Day, 2010 and World Congress of Fetal Medicine, Greece, June, 2010.

Crane J, Keough M, Murphy P, Burrage L, Hutchens D. Effects of Environmental Tobacco Smoke on Perinatal Outcomes –  Presented Society of Obstetrics and Gynacologists of Canada, Annual Clinical Meeting, 2010 and American College of Obstetricians and Gynecologists, Annual Clinical Meeting, 2011.

Ezzat H, Magee L, Liston R, Ross S, von Dadelszon P, for the Canadian Perinatal Network (including Crane J). Protecting Patients or a Barrier to Research? Examining the Role of Canadian Research Ethics Boards – Presented Society of Obstetrics and Gynecologists of Canada, Annual Clinical Meeting, 2010.

Fontaine D, Ratnam S, Bentley J, Escott N, Ghatage P, Holloway G, Bartellas E, Kum N, Lear A Coutlee F for the TPAPT Study Group. PMCM2/TOP2a Testing in Cervical Cancer Screening: A Multicentre Canadian Study - Presented Society of Obstetricians and Gynaecologists of Canada, Annual Clinical Meeting, 2010.

Aubrey-Bassler K, Wang P, Simms A, Crane J, Godwin M, Cullen R, Weaver B. Residential Proximity and Hospital Level of Service: A Geospatial Epidemiological Study of Obstetrical Outcomes - Presented North American Primary Care Research Group, 2010.

Crane JM, Hutchens D. Transvaginal Ultrasonography in Asymptomatic High Risk Women with a Short Cervical Length in the Previous Pregnancy - Presented International Society of Ultrasound in Obstetrics and Gynecology 2010.

Popadiuk C, Rose J.  Does delaying the onset of pap smear screening in Newfoundland (NL) impact cervical cancer rates? – Presented 2010 ASCO Annual Meeting Abstract No: e12002.

Popadiuk C, Andrews P, Kao K.  Increased Expression of hPygo2 is a cellular   response to HPV infection in cervical dysplasia. Presented Experimental Biology 2010 – American Society of Investigative Pathology. 

Popadiuk C, Andrews P, Kao K.  Pygopus is essential for ribosome biogenesis in cancer. Presented  Cancer & Metabolism – Pathways to the Future, 2010.

Popadiuk C, Andrews P, Kao K.  Correlation of Pygopus protein expression with cancer cell cycle progression. Presented  3rd Oncology Biomarkers Conference, 2011.

Popadiuk C, Andrews P, Kao K.  Cooperative regulation of hPgyo2 biomarker expression in cervical dysplasia and cancer. Presented  Society Gynecologic Oncology, 2011.

Popadiuk C, Andrews P, Kao K.  Gain-of-function Wnt-Independent Activity of the Pygopus2 Transcription Factor in Gynecologic Cancer. Presented Eurogin, 2011.

Yeung P,  Tu F, Lamvu G, Sinervo K, Winer W, Albee R, Bajzak K (site investigator), Strand T (site), Hutchens D (site). Characteristics of Patient Population with Endometriosis: A Pilot Study.

Barrett J (Crane J- site investigator). The Twin Birth Study (TBS) – Canadian Institute of Health Research Grant.

Avery S, Dawson L. A Retrospective Study on Wait Times for Pelvic Ultrasound in Women Diagnosed with Ovarian Cancer: Do Wait Times in NL Meet the Provincial Standard as Determined by Professional Opinion? – Presented Discipline Obstetrics and Gynecology, Memorial University of Newfoundland, Annual Resident Research Day, 2011.

Bartellas E. Breakage and Retention of a Nova T Intrauterine Device: A Rare Complication -  Presented Discipline Obstetrics and Gynecology, Memorial University of Newfoundland, Annual Resident Research Day, 2011.

Power P, Ross E, Turner F, Kirby F. Ovarian Cancer: What Obstericians and Gynecologists Need to Know and the Importance of Their Role – Presented Society of Obstetricians and Gynecologists of Canada, Annual Clinical Meeting, 2011.

Crane J, Magee LA, von Dadelszen P, Bujold E, for the Canadian Perinatal Network Collaborative Group. Between-Centre Variation in Perinatal and Maternal Outcomes of Women Presenting With Very Preterm Labour – Presented Society of Obstetricians and Gynecologists of Canada, Annual Clinical Meeting, 2011 and Society of Maternal Fetal Medicine, Annual Clinical Meeting, 2011.

Chen I, Bajzak K, Sing S. A National Survey of Endoscopic Practice Among Obstetrician-Gynecologists in Canada – Presented Society of Obstetricians and Gynecologists of Canada, Annual Clinical Meeting, 2011.

Crane J, O’Grady T, Splinter K, Hutchens D. Transvaginal Ultrasonography to Predict Preterm Birth in Women with Hysteroscopic Uterine Septum Resection - Presented International Society of Ultrasound in Obstetrics and Gynecology 2011 and submitted for publication.

Popadiuk C, Stankiewicz A, Dickinson J, Pogany L, Onysko J, Ahmed R, Miller AB.  Invasive Cervical Cancer Incidence and Mortality among Canadian Women aged 15 to 29: 1970-2007.  Presented  27th International Papillomavirus Conference, 2011. Submitted for publication.

Tzenov J, Kao K, Popadiuk C.  Cervical Adeno-carcinoma Disease Progression. Presented  27th International Papillomavirus Conference, 2011.

Popadiuk C, Gullison B, Rose J.  Cervical Cancer in Newfoundland and Labrodar, Canada:  An Audit of Diagnosis, Pap Smear History and Screening Rates. Presented 17th International Meeting of the European Society of Gynaecological Oncology, 2011.

Andrews PGP, HE Z, Tzenov YR, Popadiuk C, and Kao KR.  Activation of oncogenic ribosomal gene transcription requires Pygopus– dependent Histone H4 acetylation at the rDNA promoter.  In final revision Nucleic Acid Research.

Tzenov Y, Andrews PG,  Xiong J, Nicholas C, Pater A, Kao K, Popadiuk C.  HPV E7-mediated degradation of Rb induces hPygopus2 expression through Elf-1. Presented  27th International Papillomavirus Conference, 2011. Manuscript in preparation.

Crane JMG, Scott H, A Stewart, Whittle W, Chandra S, Hutchens D. Transvaginal ultrasonography in the prediction of preterm birth in women with a uterine anomaly. Prepared for publication.

Dickinson J, Stankiewicz A, Popadiuk C, Pogany L, Onysko J, Miller AB.  Reduced Incidence and Mortality from Cervical Cancer in Canada.  Submitted for publication.

Ongoing

Chandra S, Crane J, Sawwan E, Hutchens D. Predicting Successful Labor Induction with a Bedside Biochemical Test. Canadian Foundation for Women’s Health Grant.

Liston R, Magee L, Lee S, von Dadelszen P, Ansermino M, Barrett J, Smith G, Walker M, Allen V, Piedboeuf, Crane J(site). Birth under 29 weeks: Improving Outcomes for Mothers and Babies – Canadian Institute of Health Researchand Janeway Research Advisory Committee Grants.

Magee L, Crane J (site). The Control of Hypertension in Pregnancy Study (CHIPS) – Canadian Institute of Health Research Grant.

Lee S, Murphy P (site), Crane J (site). Survey of Mode of Delivery and Maternal and Perinatal Outcomes in Canada – Canadian Institute of Health Research Grant.

Newhook L, Sloka S, Twells L, Stokes, Murphy P, MacDonald D, Alaghebandan R, Halfyard B, Crane J, Kovacs G. Is vitamin D deficiency or insufficiency in early pregnancy associated with maternal adverse health outcomes?

Kleinrouweier E, Crane J. PRODUCE – Prediction of Preterm Delivery by Ultrasound measurement of cervical length.

Power P (site). A Randomized, Double-Blind, Placebo Controlled, Phase II Trial of Paclitaxel in Combination with AMG 386 in Subjects with Advanced Recurrent Epithelial Ovarian or Primary Peritoneal Cancer.

Power P. EN.7 Study - Randomized Phase III Trial Comparing Concurrent Chemoradiation and Adjuvant Chemotherapy with Pelvic Radiation Alone in High Risk and Advanced Stage Endometrial Carcinoma. .

Power P (site). OV.21 – A Phase II/II Study of Intraperitoneal (IP) Plus Intravenous (IV) Chemotherapy versus IV Carboplatin Plus Paclitaxel in Patients with Epithelial Ovarian Cancer Optimally Debulked at Surgery Following Neoadjuvant Intravenous Chemotherapy.

Power, P, Dawson L. The Sensitivity of HPV and Biomarker Testing of Urine Samples in a Colposcopy Clinic Population – Cancer Care Foundation Grant.

Dawson L. The Clinical Profile of Ovarian Cancer in Women with MSH2 Lynch Syndrome Mutation in Newfoundland.

New

Bajzak K. Does Training with Nintendo Wii Console Improve Laparoscopy Skills in Medical Students? A Randomized Controlled Study. – Health Care Foundation Grant.

Crane J. Survey of Maternal Fetal Medicine Practice of Assessment of Fetal Lung Maturity.

Crane J. The Effects Antenatal Corticosteroids on Neonates Born Before 24 Weeks Gestation.

Mayrand MH, Power P (site). Randomized Controlled Trial Comparing Routine Colposcopy to HPV Testing to Identify persistent or Recurrent High Grade Cervical Cancer precursors (CoHIPP) – Terry Fox Foundation Grant.

Walker M, Wen S, Crane J (site). Effect of Folic Acid Supplementation in Pregancy on Preeclampsia – Folic Acid Clinical Trial (FACT) - Canadian Institute of Health Research Grant.