Research
Peer Reviewed Publications & Research Activities
2023
Everard K, Ikpatt O, Pirzada A. Primary follicular lymphoma of the colon presenting as an incidental finding on endoscopy. J Case Rep Images Pathol 2023;9(2):1–4.
Brennan, H., Kirby, S. The role of artificial intelligence in the treatment of obstructive sleep apnea. J of Otolaryngol - Head & Neck Surg 52, 7 (2023). https://doi.org/10.1186/s40463-023-00621-0
Brennan, H., Kirby, S. Intraoperative video recording in otolaryngology for surgical education: evolution and considerations. J of Otolaryngol - Head & Neck Surg 52, 2 (2023). https://doi.org/10.1186/s40463-023-00620-1
Pearson, P., Smith, K., Sood, N., Kirby, S. et al. Kruppel-family zinc finger proteins as emerging epigenetic biomarkers in head and neck squamous cell carcinoma. J of Otolaryngol - Head & Neck Surg 52, 41 (2023). https://doi.org/10.1186/s40463-023-00640-x
Singh S, Penney C, Griffin A, Woodland G, Werdyani S, Benteau TA, Abdelfatah N, Squires J, King B, Houston J, Dyer MJ, Roslin NM, Vincent D, Marquis P, O'Rielly DD, Hodgkinson K, Burt T, Baker A, Stanton SG, Young TL. Highly variable hearing loss due to POU4F3 (c.37del) is revealed by longitudinal, frequency specific analyses. Eur J Hum Genet. 2023 Jul;31(7):815-823. doi: 10.1038/s41431-023-01358-0. Epub 2023 Apr 19. PMID: 37072551; PMCID: PMC10325993.
Roy SF, Baig J, DeCoste R, Finch S, Sennik S, Kakadekar A, Sade S, Micevic G, Chergui M, Rahimi K, Flaman A, Trinh VQH, Osmond A. Tumour necrosis is a valuable histopathological prognostic parameter in melanomas of the vulva and vagina. Pathology. 2024 May 28: S0031-3025(24)00136-3. doi: 10.1016/j.pathol.2024.03.008. Epub ahead of print. PMID: 38906758.
Roebothan A, Smith KN, Seal M, Etchegary H, Dawson L. Specialty Care and Counselling about Hereditary Cancer Risk Improves Adherence to Cancer Screening and Prevention in Newfoundland and Labrador Patients with BRCA1/2 Pathogenic Variants: A Population-Based Retrospective Cohort Study. Curr Oncol. 2023 Oct 22;30(10):9367-9381. doi: 10.3390/curroncol30100678. PMID: 37887578; PMCID: PMC10605144.
Nunn A, Morrissey A, Crocker A, Patterson K, Stares J, Smith K, Gilbert L, Wilkinson K. Community-based COVID-19 outbreak of the B.1.1.7 (Alpha) variant of concern in Newfoundland, February to March 2021. Can Commun Dis Rep. 2023 Feb 1;49(2-3):59-66. PMID: 38090726; PMCID: PMC10715830.
Gill IS, Griffiths EJ, Dooley D, Cameron R, Savić Kallesøe S, John NS, Sehar A, Gosal G, Alexander D, Chapel M, Croxen MA, Delisle B, Di Tullio R, Gaston D, Duggan A, Guthrie JL, Horsman M, Joshi E, Kearny L, Knox N, Lau L, LeBlanc JJ, Li V, Lyons P, MacKenzie K, McArthur AG, Panousis EM, Palmer J, Prystajecky N, Smith KN, Tanner J, Townend C, Tyler A, Van Domselaar G, Hsiao WWL. The DataHarmonizer: a tool for faster data harmonization, validation, aggregation and analysis of pathogen genomics contextual information. Microb Genom. 2023 Jan;9(1): mgen000908. doi: 10.1099/mgen.0.000908. PMID: 36748616; PMCID: PMC9973856.
Shaw JLV, Arnoldo S, Beach L, Bouhtiauy I, Brinc D, Brun M, Collier C, Kostantin E, Fung AWS, Füzéry AK, Huang Y, Kaur S, Knauer M, Labrecque L, Leung F, Shea JL, Thakur V, Thorlacius L, Venner AA, Yip PM, De Guire V. Establishing quality indicators for point of care glucose testing: recommendations from the Canadian Society for Clinical Chemists Point of Care Testing and Quality Indicators Special Interest Groups. Clin Chem Lab Med. 2023 Apr 12;61(7):1280-1287. doi: 10.1515/cclm-2023-0147. PMID: 37043622.
Zern C, Tate A, Pirzada A, Burrage K, Grewal K, & Ikpatt O. Peripheral lymphadenopathy as initial presentation of hairy cell leukemia. Canadian Journal of Pathology. May 2023, Vol. 15 Issue 2, p37-31.
Zern, C, Ikpatt, O, O’Rielly, D. Molecular Landscape of Newly Diagnosed Acute Myeloid Leukemia Cases in Newfoundland and Labrador from 2019-2023.
Everard, K, Zern, C, Ikpatt, O. Plasma Cell Neoplasms with Atypical Features in a University Hospital. Submitted to the e Journal of Hematology.
Everard, K, Zern, C, Ikpatt, O. Extramedullary Acute Undifferentiated Leukemia Presenting in the Skin and Lymph Nodes. Submitted to the e Journal of Hematology.
Everard K, Zern, C, Ikpatt, O. Splenectomies in Newfoundland and Labrador, Canada: A 10-year Evaluation. Accepted to the Canadian Journal of Pathology.
O’Brien, J, Zern, C, Ikpatt, O. Primary Testicular Lymphoma in Newfoundland and Labrador, Canada: A 10-year Evaluation. Submitted to Elsevier Pathology.
2022
Marques-Garcia F, Boned B, González-Lao E, Braga F, Carobene A, Coskun A, Díaz-Garzón J, Fernández-Calle P, Perich MC, Simon M, Jonker N, Aslan B, Bartlett WA, Sandberg S, Aarsand AK; European Federation of Clinical Chemistry and Laboratory Medicine Working Group on Biological Variation and Task Group for the Biological Variation Database. Critical review and meta-analysis of biological variation estimates for tumor markers. Clin Chem Lab Med. 2022 Feb 10;60(4):494-504. doi: 10.1515/cclm-2021-0725. PMID: 35143717.
Rutledge AC, Johnston A, Booth RA, Veljkovic K, Bailey D, Vandenberghe H, Waite G, Allen LC, Don-Wauchope A, Chan PC, Stemp J, Edmond P, Leung V, Aslan B. Lot verification practices in Ontario clinical chemistry laboratories Results of a patterns-of-practice survey. Pract Lab Med. 2022 Aug 10;32: e00300. doi: 10.1016/j.plabm. 2022 e00300. PMID: 36035320; PMCID: PMC9399155.
Galloway DA, Carew SJ, Blandford SN, Benoit RY, Fudge NJ, Berry T, Moore GRW, Barron J, Moore CS. Investigating the NLRP3 inflammasome and its regulator miR-223-3p in multiple sclerosis and experimental demyelination. J Neurochem. 2022 Oct;163(2):94-112. doi: 10.1111/jnc.15650. Epub 2022 Jun 7. PMID: 35633501.
Loyzer MN, Grewal K, Ikpatt OF. Plasma cell myeloma following a prior diagnosis of chronic lymphocytic leukemia/small lymphocytic lymphoma. Clin Case Rep. 2022 Dec 18;10(12): e6722. doi: 10.1002/ccr3.6722. PMID: 36545556; PMCID: PMC9760783.
Loyzer MN, Musadak H, Ikpatt OF. Chronic myeloid leukemia, BCR-ABL1-positive, presenting in a previously healthy infant. Canadian Journal of Pathology 2022; 14(4): 28-32.
Fitzpatrick M, Pirzada A, Ikpatt O (2022) Crystal-Storing Histiocytosis in a Patient with Nodal Marginal Zone Lymphoma. Int J Pediatr Res 8:142. doi.org/10.23937/2469-5807/1510142
Brennan HL, Kirby SD. Barriers of artificial intelligence implementation in the diagnosis of obstructive sleep apnea. J Otolaryngol Head Neck Surg. 2022 Apr 25;51(1):16. doi: 10.1186/s40463-022-00566-w. PMID: 35468865; PMCID: PMC9036782.
Bohn MK, Wilson S, Schneider R, Massamiri Y, Randell EW, Adeli K. Pediatric reference interval verification for 17 specialized immunoassays and cancer markers on the Abbott Alinity i system in the CALIPER cohort of healthy children and adolescents. Clin Chem Lab Med. 2022 Sep 19;61(1):123-132. doi: 10.1515/cclm-2022-0709. PMID: 36117243; PMCID: PMC9691267.
Grafodatskaya D, O'Rielly DD, Bedard K, Butcher DT, Howlett CJ, Lytwyn A, McCready E, Parboosingh J, Spriggs EL, Vaags AK, Stockley TL. Practice guidelines for BRCA1/2 tumour testing in ovarian cancer. J Med Genet. 2022 Aug;59(8):727-736. doi: 10.1136/jmedgenet-2021-108238. Epub 2022 Apr 7. PMID: 35393334; PMCID: PMC9340048.
Pater JA, Penney C, O'Rielly DD, Griffin A, Kamal L, Brownstein Z, Vona B, Vinkler C, Shohat M, Barel O, French CR, Singh S, Werdyani S, Burt T, Abdelfatah N, Houston J, Doucette LP, Squires J, Glaser F, Roslin NM, Vincent D, Marquis P, Woodland G, Benoukraf T, Hawkey-Noble A, Avraham KB, Stanton SG, Young TL. Autosomal dominant non-syndromic hearing loss maps to DFNA33 (13q34) and co-segregates with splice and frameshift variants in ATP11A, a phospholipid flippase gene. Hum Genet. 2022 Apr;141(3-4):431-444. doi: 10.1007/s00439-022-02444-x. Epub 2022 Mar 12. PMID: 35278131; PMCID: PMC9035003.
Woodbury-Smith M, Lamoureux S, Begum G, Nassir N, Akter H, O'Rielly DD, Rahman P, Wintle RF, Scherer SW, Uddin M. Mutational Landscape of Autism Spectrum Disorder Brain Tissue. Genes (Basel). 2022 Jan 24;13(2):207. doi: 10.3390/genes13020207. PMID: 35205252; PMCID: PMC8871846.
Gill SJ, Pirzada A, Power P, Neveu J. A Constellation of Rare Gynecological Malignancies and Familial Adenomatous Polyposis Gastrointestinal Adenocarcinoma: A Case Report. Int J Gynecol Pathol. 2022 Nov 1;41(6):622-627. doi: 10.1097/PGP.0000000000000836. Epub 2021 Dec 1. PMID: 36302191.
Liu M, Huang Y, Zhang H, Aitken D, Nevitt MC, Rockel JS, Pelletier JP, Lewis CE, Torner J, Rampersaud YR, Perruccio AV, Mahomed NN, Furey A, Randell EW, Rahman P, Sun G, Martel-Pelletier J, Kapoor M, Jones G, Felson D, Qi D, Zhai G. Restricting Branched-Chain Amino Acids within a High-Fat Diet Prevents Obesity. Metabolites. 2022 Apr 7;12(4):334. doi: 10.3390/metabo12040334. PMID: 35448521; PMCID: PMC9030079.
Werdyani S, Aitken D, Gao Z, Liu M, Randell EW, Rahman P, Jones G, Zhai G. Metabolomic signatures for the longitudinal reduction of muscle strength over 10 years. Skelet Muscle. 2022 Feb 7;12(1):4. doi: 10.1186/s13395-022-00286-9. PMID: 35130970; PMCID: PMC8819943.
Alexander DC, Taylor RM, Martin I, Adam H, Lagacé-Wiens P, Pieroni P, Karlowsky JA, Van Caeseele P. Evaluation of the Hologic Aptima Combo 2 Assay for Detection of Neisseria gonorrhoeae from Joint Fluid Specimens. J Clin Microbiol. 2022 Apr 20;60(4): e0253021. doi: 10.1128/jcm.02530-21. Epub 2022 Mar 23. PMID: 35317619; PMCID: PMC9020330.
Nichols JH, Ali M, Anetor JI, Chen LS, Chen Y, Collins S, Das S, Devaraj S, Fu L, Karon BS, Kary H, Nerenz RD, Rai AJ, Shajani-Yi Z, Thakur V, Wang S, Yu HYE, Zamora LE. AACC Guidance Document on the Use of Point-of-Care Testing in Fertility and Reproduction. J Appl Lab Med. 2022 Sep 1;7(5):1202-1236. doi: 10.1093/jalm/jfac042. PMID: 36047824.
Thakur V, Anthony Akerele O, Brake N, Wiscombe M, Broderick S, Campbell E, Randell E. Use of a Lean Six Sigma approach to investigate excessive quality control (QC) material use and resulting costs. Clin Biochem. 2023 Feb; 112:53-60. doi: 10.1016/j.clinbiochem.2022.12.001. Epub 2022 Dec 10. PMID: 36513121.
Demczuk W, Martin I, Griffith A, Lefebvre B, McGeer A, Tyrrell GJ, Zhanel GG, Kus JV,Hoang L, Minion J, Van Caeseele P, Gad RR, Haldane D, Zahariadis G, Mead K, Steven L, Strudwick L, Mulvey MR. 2022. Linear Regression Equations to Predict β-Lactam, Macrolide, Lincosamide, and Fluoroquinolone MICs from Molecular Antimicrobial Resistance Determinants in Streptococcus pneumoniae. Antimicrob Agents Chemother 66: e01370-21. https://doi.org/10.1128/AAC.01370-21
Bharat A, Petkau A, Avery BP, Chen JC, Folster JP, Carson CA, Kearney A, Nadon C, Mabon P, Thiessen J, Alexander DC, Allen V, El Bailey S, Bekal S, German GJ, Haldane D, Hoang L, Chui L, Minion J, Zahariadis G, Domselaar GV, Reid-Smith RJ, Mulvey MR. Correlation between Phenotypic and In Silico Detection of Antimicrobial Resistance in Salmonella enterica in Canada Using Staramr. Microorganisms. 2022; 10(2):292. https://doi.org/10.3390/microorganisms10020292
2021
Cheng A, Barron J, Holmes O, Bartlett P, Jenkins G, Seal M. Primary neuroendocrine tumor of the pineal gland: a case report. BMC Neurol. 2021 Aug 20;21(1):323. doi: 10.1186/s12883-021-02351-0. PMID: 34416869; PMCID: PMC8377818.
Fasih S, Suppiyah S, Barron J, Barnett-Tapia C, Avery R, Dickson B, Ferguson P, Swallow C, Zadeh G, Gupta AA. Malignant transformation of plexiform neurofibroma to MPNST while on MEK inhibitor. Neurooncol Adv. 2021 Feb 23;3(1): vdab033. doi: 10.1093/noajnl/vdab033. PMID: 33959714; PMCID: PMC8086239.
Erivwo, P., Armstrong, S., Bokenfohr, R., Mrkonjic, M., Turashvili. G., Point-Based Weighted Diagnostic Scale for Histopathologic Assessment of Mammary Cellular Fibroepithelial Lesions. Abstracts and Case Studies from the College of American Pathologists 2021 Annual Meeting (CAP '21). Archives of Pathology & Laboratory Medicine: Sep 2021, Vol. 145, No. 9, pp. e115
Erivwo P, Turashvili G. Pathology of IgG4-related sclerosing mastitis. J Clin Pathol. 2021 Aug;74(8):475-482. doi: 10.1136/jclinpath-2020-207029. Epub 2020 Dec 16. Erratum in: J Clin Pathol. 2021 Dec;74(12): e16. PMID: 33328182.
Abdelfatah N, Mostafa AA, French CR, Doucette LP, Penney C, Lucas MB, Griffin A, Booth V, Rowley C, Besaw JE, Tranebjærg L, Rendtorff ND, Hodgkinson KA, Little LA, Agrawal S, Parnes L, Batten T, Moore S, Hu P, Pater JA, Houston J, Galutira D, Benteau T, MacDonald C, French D, O'Rielly DD, Stanton SG, Young TL. A pathogenic deletion in Forkhead Box L1 (FOXL1) identifies the first otosclerosis (OTSC) gene. Hum Genet. 2022 Apr;141(3-4):965-979. doi: 10.1007/s00439-021-02381-1. Epub 2021 Oct 11. PMID: 34633540; PMCID: PMC9034980.
O'Rielly DD, Rahman P. Clinical and molecular significance of genetic loci associated with psoriatic arthritis. Best Pract Res Clin Rheumatol. 2021 Jun;35(2):101691. doi: 10.1016/j.berh.2021.101691. Epub 2021 May 19. PMID: 34020887.
O'Rielly DD, Rahman P. Genetic Epidemiology of Complex Phenotypes. Methods Mol Biol. 2021; 2249:335-367. doi: 10.1007/978-1-0716-1138-8_19. PMID: 33871853
Akter H, Hossain MS, Dity NJ, Rahaman MA, Furkan Uddin KM, Nassir N, Begum G, Hameid RA, Islam MS, Tusty TA, Basiruzzaman M, Sarkar S, Islam M, Jahan S, Lim ET, Woodbury-Smith M, Stavropoulos DJ, O'Rielly DD, Berdeiv BK, Nurun Nabi AHM, Ahsan MN, Scherer SW, Uddin M. Whole exome sequencing uncovered highly penetrant recessive mutations for a spectrum of rare genetic pediatric diseases in Bangladesh. NPJ Genom Med. 2021 Feb 16;6(1):14.
Randell EW, Thakur V. Leading POCT Networks: Operating POCT Programs Across Multiple Sites Involving Vast Geographical Areas and Rural Communities. EJIFCC. 2021 Jun 29;32(2):179-189. PMID: 34421486; PMCID: PMC8343053.
Taher J, Randell EW, Arnoldo S, Bailey D, De Guire V, Kaur S, Knauer M, Petryayeva E, Poutanen SM, Shaw JLV, Uddayasankar U, White-Al Habeeb N, Konforte D. Canadian Society of Clinical Chemists (CSCC) consensus guidance for testing, selection and quality management of SARS-CoV-2 point-of-care tests. Clin Biochem. 2021 Sep;95: 1-12. doi: 10.1016/j.clinbiochem.2021.05.010. Epub 2021 May 25. PMID: 34048776; PMCID: PMC8144094.
Bohn MK, Wilson S, Hall A, Massamiri Y, Randell E, Adeli K. Pediatric reference interval verification for common biochemical assays on the Abbott Alinity system. Clin Chem Lab Med. 2021 May 19;59(9):1554-1562. doi: 10.1515/cclm-2021-0336. PMID: 34008378; PMCID: PMC9577062.
Gao X, Du L, Randell E, Zhang H, Li K, Li D. Effect of different phosphatidylcholines on high fat diet-induced insulin resistance in mice. Food Funct. 2021 Mar 1;12(4):1516-1528. doi: 10.1039/d0fo02632h. PMID: 33506827.
Pan F, Liu M, Randell EW, Rahman P, Jones G, Zhai G. Sphingomyelin is involved in multisite musculoskeletal pain: evidence from metabolomic analysis in 2 independent cohorts. Pain. 2021 Jun 1;162(6):1876-1881. doi: 10.1097/j.pain.0000000000002163. PMID: 33273416.
Werdyani S, Liu M, Zhang H, Sun G, Furey A, Randell EW, Rahman P, Zhai G. Endotypes of primary osteoarthritis identified by plasma metabolomics analysis. Rheumatology (Oxford). 2021 Jun 18;60(6):2735-2744. doi: 10.1093/rheumatology/keaa693. PMID: 33159799; PMCID: PMC8213424.
Liu M, Xie Z, Costello CA, Zhang W, Chen L, Qi D, Furey A, Randell EW, Rahman P, Zhai G. Metabolomic analysis coupled with extreme phenotype sampling identified that lysophosphatidylcholines are associated with multisite musculoskeletal pain. Pain. 2021 Feb 1;162(2):600-608. doi: 10.1097/j.pain.0000000000002052. PMID: 32833795; PMCID: PMC7808366.
Zhai G, Sun X, Randell EW, Liu M, Wang N, Tolstykh I, Rahman P, Torner J, Lewis CE, Nevitt MC, Guermazi A, Roemer F, Felson DT. Phenylalanine Is a Novel Marker for Radiographic Knee Osteoarthritis Progression: The MOST Study. J Rheumatol. 2021 Jan 1;48(1):123-128. doi: 10.3899/jrheum.200054. Epub 2020 May 1. PMID: 32358162; PMCID: PMC8039838.
Mu X, Fardy J, Reid S, Trahey J. Severe drug-associated colitis with Crohn's features in setting of ixekizumab therapy for chronic plaque psoriasis. BMC Gastroenterol. 2021 Oct 2;21(1):361. doi: 10.1186/s12876-021-01936-w. PMID: 34600483; PMCID: PMC8487480.
Shivji S, Kak I, Reid SL, Muir J, Hafezi-Bakhtiari S, Li-Chang H, Deliallisi A, Newell KJ, Grin A, Conner J, Kirsch R. Feasibility and Performance of Elastin Trichrome as a Primary Stain in Colorectal Cancer Resection Specimens: Results of an Interobserver Variability Study. Am J Surg Pathol. 2021 Oct 1;45(10):1419-1427. doi: 10.1097/PAS.0000000000001707. PMID: 33756495.
Taylor RM, Karlowsky JA, Baxter MR, Adam HJ, Walkty A, Lagacé-Wiens P, Zhanel GG. In vitro susceptibility of common bacterial pathogens causing respiratory tract infections in Canada to lefamulin, a new pleuromutilin. J Assoc Med Microbiol Infect Dis Can. 2021 Jul 20;6(2):149-162. doi: 10.3138/jammi-2020-0043. PMID: 36341032; PMCID: PMC9608697.
Misra A, Speicher DJ, Luinstra K, Maciejewski J, Richard-Greenblatt M, Yu Y, Smieja M. Self-collected oral flocked swabs to measure prevalence of Epstein-Barr Virus antibodies and DNA amongst university students. Diagn Microbiol Infect Dis. 2021 May;100(1):115295. doi: 10.1016/j.diagmicrobio.2020.115295. Epub 2020 Dec 24. PMID: 33497868.
Needle R, Gilbert L, Zahariadis G, Yu Y, Dalton-Kenny H, Russell RS, Wang P, Donovan C, Hookey S, Jiao L. Serological Evaluation of Human Antibodies of the Immunoglobulin Class A and G Against SARS-CoV-2 in Serum Collected in Newfoundland and Labrador. Viral Immunol. 2021 Apr;34(3):182-189. doi: 10.1089/vim.2020.0199. Epub 2021 Mar 18. PMID: 33739895.
Cox GW, Parmley EJ, Avery BP, Irwin RJ, Reid-Smith RJ, Deckert AE, Finley RL, Daignault D, Alexander DC, Allen V, El Bailey S, Bekal S, Chui L, German GJ, Haldane D, Hoang L, Minion J, Zahariadis G, Mulvey MR, Bharat A. A One-Health Genomic Investigation of Gentamicin Resistance in Salmonella from Human and Chicken Sources in Canada, 2014 to 2017. Antimicrob Agents Chemother. 2021 Nov 17;65(12): e0096621. doi: 10.1128/AAC.00966-21. Epub 2021 Sep 27. PMID: 34570642; PMCID: PMC8597779.
Stein DR, Osiowy C, Gretchen A, Thorlacius L, Fudge D, Lang A, Sekirov I, Morshed M, Levett PN, Tran V, Kus JV, Gubbay J, Mohan V, Charlton C, Kanji JN, Tipples G, Serhir B, Therrien C, Roger M, Jiao L, Zahariadis G, Needle R, Gilbert L, Desnoyers G, Garceau R, Bouhtiauy I, Longtin J, El-Gabalawy N, Dibernardo A, Lindsay LR, Drebot M; Canadian Public Health Laboratory Network (CPHLN) Serology Task Force. Evaluation of commercial SARS-CoV-2 serological assays in Canadian public health laboratories. Diagn Microbiol Infect Dis. 2021 Nov;101(3):115412. doi: 10.1016/j.diagmicrobio.2021.115412. Epub 2021 Apr 24. PMID: 34425450; PMCID: PMC8377389.
Chung H, Buchan SA, Campigotto A, Campitelli MA, Crowcroft NS, Dubey V, Gubbay JB, Karnauchow T, Katz K, McGeer AJ, McNally JD, Mubareka S, Murti M, Richardson DC, Rosella LC, Schwartz KL, Smieja M, Zahariadis G, Kwong JC. Influenza Vaccine Effectiveness Against All-Cause Mortality Following Laboratory-Confirmed Influenza in Older Adults, 2010-2011 to 2015-2016 Seasons in Ontario, Canada. Clin Infect Dis. 2021 Sep 7;73(5): e1191-e1199. doi: 10.1093/cid/ciaa1862. PMID: 33354709; PMCID: PMC8423473.
Gilbert L, Ratnam S, Jang D, Alaghehbandan R, Schell M, Needle R, Ecobichon-Morris A, Wadhawan A, Costescu D, Elit L, Wang P, Zahariadis G, Chernesky M. Comparison of CINtec PLUS cytology and cobas HPV test for triaging Canadian patients with LSIL cytology referred to colposcopy: A two-year prospective study. Cancer Biomark. 2022;34(3):347-358. doi: 10.3233/CBM-210366. PMID: 35001877; PMCID: PMC9535599.
Ratnam S, Jang D, Gilbert L, Alaghehbandan R, Schell M, Needle R, Ecobichon-Morris A, Wang PP, Rahman M, Costescu D, Elit L, Zahariadis G, Chernesky M. Corrigendum to CINtec PLUS and cobas HPV testing for triaging Canadian women referred to colposcopy with a history of low-grade squamous intraepithelial lesion: Baseline findings [Papillomavirus Res. 10 (2020) 100206]. Tumour Virus Res. 2021 Jun; 11:200215. doi: 10.1016/j.tvr.2021.200215. Epub 2021 Mar 17. Erratum for: Papillomavirus Res. 2020 Dec; 10:100206. doi: 10.1016/j.pvr.2020.100206. PMID: 33741546; PMCID: PMC8010203.
Sanyaolu A, Zern C, Fletcher A, Ghelmegeanu D, Roth D, Lapuz A, Massengale M, Higgins A, & Alaofin C. Feb 2021. Epidemiology of Injection Drug Use among Teenagers with HIV and Hepatitis in the US. Journal of Infectious Disease & Travel Medicine. 5(1).
2020
Hart S, Avery R, Barron J. Late recurrence of choroid plexus carcinoma. Childs Nerv Syst. 2020 Aug;36(8):1601-1606. doi: 10.1007/s00381-020-04663-x. Epub 2020 May 15. PMID: 32409961.
Erivwo P, Bharatwal V, Huang M, Godra A, Turashvili G. Classic IgG4-related sclerosing mastitis is not so classic. Breast J. 2020 Jun;26(6):1245-1248. doi: 10.1111/tbj.13846. Epub 2020 Apr 20. PMID: 32311182.
Hoofd C, Huang SJ, Gusscott S, Lam S, Wong R, Johnston A, Ben-Neriah S, Steidl C, Scott DW, Bruyere H, Gillan TL, Toze CL, Gerrie AS, Weng AP. Ultrasensitive Detection of NOTCH1 c.7544_7545delCT Mutations in Chronic Lymphocytic Leukemia by Droplet Digital PCR Reveals High Frequency of Subclonal Mutations and Predicts Clinical Outcome in Cases with Trisomy 12. J Mol Diagn. 2020 Apr;22(4):571-578. doi: 10.1016/j.jmoldx.2020.01.008. Epub 2020 Feb 6. PMID: 32036086.
States A, Kirby S. Benign Palatine Tonsil Volume Variation Following Bilateral Tonsillectomy in Adults. Cureus. 2020 Mar 16;12(3): e7288. doi: 10.7759/cureus.7288. PMID: 32300507; PMCID: PMC7159142.
Truong T, Kirby SD. Factors Affecting Diagnostic Discordance in Intraoperative Frozen Section Diagnosis:An Institutional Experience. Can Journal of Pathology Vol 12(2), May 2020. pp. 31-44
J. Vidal, R. Ndikumana, K. Whelan, J. Whelan. Delayed lung adenocarcinoma metastasis to the choroid in a non-end- stage cancer patient; Journal: Canadian Journal of Ophthalmology. Feb 18, 2020.
Costello CA, Hu T, Liu M, Zhang W, Furey A, Fan Z, Rahman P, Randell EW, Zhai G. Differential correlation network analysis identified novel metabolomics signatures for non-responders to total joint replacement in primary osteoarthritis patients. Metabolomics. 2020 Apr 25;16(5):61. doi: 10.1007/s11306-020-01683-1. PMID: 32335722; PMCID: PMC7183485.
Liu M, Xie Z, Costello CA, Zhang W, Chen L, Qi D, Furey A, Randell EW, Rahman P, Zhai G. Metabolomic analysis coupled with extreme phenotype sampling identified that lysophosphatidylcholines are associated with multisite musculoskeletal pain. Pain. 2021 Feb 1;162(2):600-608. doi: 10.1097/j.pain.0000000000002052. PMID: 32833795; PMCID: PMC7808366.
Bailey D, Konforte D, Barakauskas VE, Yip PM, Kulasingam V, Abou El Hassan M, Beach LA, Blasutig IM, Catomeris P, Dooley KC, Gong Y, Kavsak P, Randell EW, Robinson JL, Shaw J, Taher J, White-Al Habeeb N. Canadian society of clinical chemists (CSCC) interim consensus guidance for testing and reporting of SARS-CoV-2 serology. Clin Biochem. 2020 Dec; 86:1-7. doi: 10.1016/j.clinbiochem.2020.09.005. Epub 2020 Oct 6. PMID: 33031819; PMCID: PMC7536550.
Zhai G, Sun X, Randell EW, Liu M, Wang N, Tolstykh I, Rahman P, Torner J, Lewis CE, Nevitt MC, Guermazi A, Roemer F, Felson DT. Phenylalanine Is a Novel Marker for Radiographic Knee Osteoarthritis Progression: The MOST Study. J Rheumatol. 2021 Jan 1;48(1):123-128. doi: 10.3899/jrheum.200054. Epub 2020 May 1. PMID: 32358162; PMCID: PMC8039838.
Barrett BJ, Randell EW, Mariathas HH, Mohammadi A, Darcy S, Wilson R, Brian Johnston K, Parfrey PS. The effect of laboratory requisition modification, audit and feedback with academic detailing or both on utilization of blood urea testing in family practice in Newfoundland, Canada. Clin Biochem. 2020 Sep; 83:21-27. doi: 10.1016/j.clinbiochem.2020.05.008. Epub 2020 May 22. PMID: 32450078.
Erivwo P, Turashvili GPathology of IgG4-related sclerosing mastitisJournal of Clinical Pathology 2021;74:475-482.
Erivwo P, Bharatwal V, Huang M, Godra A, Turashvili G. Classic IgG4-related sclerosing mastitis is not so classic. Breast J. 2020 Jun;26(6):1245-1248. doi: 10.1111/tbj.13846. Epub 2020 Apr 20. PMID: 32311182.
Gao X, Sun G, Randell E, Tian Y, Zhou H. Systematic investigation of the relationships of trimethylamine N-oxide and L-carnitine with obesity in both humans and rodents. Food Funct. 2020 Sep 23;11(9):7707-7716. doi: 10.1039/d0fo01743d. PMID: 32915186.
Wadden D, Buckley A, Ghosh C, Vidyasankar G. Respiratory failure in a 28-year-old male. Breathe (Sheff). 2020 Jun;16(2):190337. doi: 10.1183/20734735.0337-2019. PMID: 33304397; PMCID: PMC7714546.
Bergstrom, D. J., Kotb, R., Louzada, M. L., Sutherland, H. J., Tavoularis, S., Venner, C. P., & Myeloma Canada Research Network Consensus Guideline Consortium. (2020). Consensus Guidelines on the Diagnosis of Multiple Myeloma and Related Disorders Myeloma Canada Research Network Consensus Guideline Consortium Recommendations. Clinical Lymphoma Myeloma and Leukemia. (Collaborators Randell EW et al.)
Werdyani S, Liu M, Zhang H, Sun G, Furey A, Randell EW, Rahman P, Zhai G. Endotypes of primary osteoarthritis identified by plasma metabolomics analysis. Rheumatology (Oxford). 2020 Nov 7: keaa693. doi: 10.1093/rheumatology/keaa693. Epub ahead of print. PMID: 33159799.
Costello CA, Hu T, Liu M, Zhang W, Furey A, Fan Z, Rahman P, Randell EW, Zhai G. Metabolomics Signature for Non-Responders to Total Joint Replacement Surgery in Primary Osteoarthritis Patients: The Newfoundland Osteoarthritis Study. J Orthop Res. 2020 Apr;38(4):793-802. doi: 10.1002/jor.24529. Epub 2019 Nov 25. PMID: 31743460.
Zhai G, Pelletier JP, Liu M, Randell EW, Rahman P, Martel-Pelletier J. Serum lysophosphatidylcholines to phosphatidylcholines ratio is associated with symptomatic responders to symptomatic drugs in knee osteoarthritis patients. Arthritis Res Ther. 2019 Nov 6;21(1):224. doi: 10.1186/s13075-019-2006-8. PMID: 31694709; PMCID: PMC6836440.
Gershon AS, Chung H, Porter J, Campitelli MA, Buchan SA, Schwartz KL, Crowcroft NS, Campigotto A, Gubbay JB, Karnauchow T, Katz K, McGeer AJ, McNally JD, Richardson DC, Richardson SE, Rosella LC, Simor AE, Smieja M, Zahariadis G, Kwong JC. Influenza Vaccine Effectiveness in Preventing Hospitalizations in Older Patients with Chronic Obstructive Pulmonary Disease. J Infect Dis. 2020 Jan 1;221(1):42-52. doi: 10.1093/infdis/jiz419. PMID: 31549165; PMCID: PMC6910872.
Tsang RSW, Shuel M, Ahmad T, Hayden K, Knox N, Van Domselaar G, Hoang L, Tyrrell GJ, Minion J, Van Caeseele P, Kus JV, Ulanova M, Lefebvre B, Haldane D, Garceau R, German G, Zahariadis G, Hanley B, Kandola K, Patterson M. Whole genome sequencing to study the phylogenetic structure of serotype a Haemophilus influenzae recovered from patients in Canada. Can J Microbiol. 2020 Feb;66(2):99-110. doi: 10.1139/cjm-2019-0406. Epub 2019 Oct 29. PMID: 31661630.
Needle R, Gilbert L, Zahariadis G, Yu Y, Dalton-Kenny H, Russell RS, Wang P, Donovan C, Hookey S, Jiao L. Serological Evaluation of Human Antibodies of the Immunoglobulin Class A and G Against SARS-CoV-2 in Serum Collected in Newfoundland and Labrador. Viral Immunol. 2021 Apr;34(3):182-189. doi: 10.1089/vim.2020.0199. Epub 2021 Mar 18. PMID: 33739895
Ratnam S, Jang D, Gilbert L, Alaghehbandan R, Schell M, Needle R, Ecobichon-Morris A, Wang PP, Rahman M, Costescu D, Elit L, Zahariadis G, Chernesky M. CINtec PLUS and cobas HPV testing for triaging Canadian women referred to colposcopy with a history of low-grade squamous intraepithelial lesion: Baseline findings. Papillomavirus Res. 2020 Dec; 10:100206. doi: 10.1016/j.pvr.2020.100206. Epub 2020 Aug 20. Erratum in: Tumour Virus Res. 2021 Jun; 11:200215. doi: 10.1016/j.tvr.2021.200215. PMID: 32828968; PMCID: PMC7548977.
LeBlanc JJ, Gubbay JB, Li Y, Needle R, Arneson SR, Marcino D, Charest H, Desnoyers G, Dust K, Fattouh R, Garceau R, German G, Hatchette TF, Kozak RA, Krajden M, Kuschak T, Lang ALS, Levett P, Mazzulli T, McDonald R, Mubareka S, Prystajecky N, Rutherford C, Smieja M, Yu Y, Zahariadis G, Zelyas N, Bastien N; COVID-19 Pandemic Diagnostics Investigation Team of the Canadian Public Health Laboratory Network (CPHLN) Respiratory Virus Working Group. Real-time PCR-based SARS-CoV-2 detection in Canadian laboratories. J Clin Virol. 2020 Jul; 128:104433. doi: 10.1016/j.jcv.2020.104433. Epub 2020 May 13. PMID: 32405254; PMCID: PMC7219382.
Kwong JC, Chung H, Jung JK, Buchan SA, Campigotto A, Campitelli MA, Crowcroft NS, Gubbay JB, Karnauchow T, Katz K, McGeer AJ, McNally JD, Richardson DC, Richardson SE, Rosella LC, Schwartz KL, Simor A, Smieja M, Zahariadis G; Canadian Immunization Research Network (CIRN) investigators. The impact of repeated vaccination using 10-year vaccination history on protection against influenza in older adults: a test-negative design study across the 2010/11 to 2015/16 influenza seasons in Ontario, Canada. Euro Surveill. 2020 Jan;25(1):1900245. doi: 10.2807/1560-7917.ES.2020.25.1.1900245. PMID: 31937397; PMCID: PMC6961264.
2019
Ma, I.; Chakrabarti, S.; Kandel, R.; Allard, M.; Barron, J.; Boag, A.; Brooks, DE.; Fischer, G.; Gaboury, L.; Gao; Z. Giguère, Y.; Magee, F.; Mengel, M.; Potter, M.; Têtu, B.; Rizcallah, E.; Sadek, I.; Veinot, JP.; Vaska, M.; Naugler, C.; Current landscape and guide to the future of molecular diagnostics and bioinformatics training for Canadian pathology residents. Can J Path. 2019 Aug: 11(3):20-39.
Ma, I.; Allard, M.; Barron, J.; Boag, A.; Chakrabarti, S.; Fischer, G.; Gaboury, L.; Gao, Z.; Kandel, R.; Magee, F.; Mengel, M.; Potter, M.; Tanguay, R.; Tetu, B.; Rizcallah, E.; Sadek, I.; Veinot, JP.; Vaska, M.; Naugler, C.; Subspecialty sign-out: a scoping review and survey of Canadian academic centres of pathology. Can J of Path. 2019 Feb: 11 (1): 28-42
Woodworth CF, Jenkins G, Barron J, Hache N. Intramedullary cervical spinal mass after stem cell transplantation using an olfactory mucosal cell autograft. CMAJ. 2019 Jul 8;191(27): E761-E764. doi: 10.1503/cmaj.181696. PMID: 31285379; PMCID: PMC6739061
Buchan SA, Chung H, Karnauchow T, McNally JD, Campitelli MA, Gubbay JB, Katz K, McGeer AJ, Richardson DC, Richardson SE, Simor A, Smieja M, Zahariadis G, Tran D, Crowcroft NS, Rosella LC, Kwong JC. Characteristics and Outcomes of Young Children Hospitalized with Laboratory-confirmed Influenza or Respiratory Syncytial Virus in Ontario, Canada, 2009-2014. Pediatr Infect Dis J. 2019 Apr;38(4):362-369. doi: 10.1097/INF.0000000000002164. PMID: 30882725.
Gao X, Randell E, Tian Y, Zhou H, Sun G. Low serum choline and high serum betaine levels are associated with favorable components of metabolic syndrome in Newfoundland population. J Diabetes Complications. 2019 Oct;33(10):107398. doi: 10.1016/j.jdiacomp.2019.06.003. Epub 2019 Jun 20. PMID: 31320248.
Gao X, Tian Y, Randell E, Zhou H, Sun G. Unfavorable Associations Between Serum Trimethylamine N-Oxide and L-Carnitine Levels with Components of Metabolic Syndrome in the Newfoundland Population. Front Endocrinol (Lausanne). 2019 Mar 26; 10:168. doi: 10.3389/fendo.2019.00168. PMID: 30972022; PMCID: PMC6443640.
Kwong JC, Buchan SA, Chung H, Campitelli MA, Schwartz KL, Crowcroft NS, Jackson ML, Karnauchow T, Katz K, McGeer AJ, McNally JD, Richardson DC, Richardson SE, Rosella LC, Simor A, Smieja M, Zahariadis G, Campigotto A, Gubbay JB. Can routinely collected laboratory and health administrative data be used to assess influenza vaccine effectiveness? Assessing the validity of the Flu and Other Respiratory Viruses Research (FOREVER) Cohort. Vaccine. 2019 Jul 18;37(31):4392-4400. doi: 10.1016/j.vaccine.2019.06.011. Epub 2019 Jun 17. PMID: 31221563.
Tsang RS, Hoang L, Tyrrell GJ, Minion J, Van Caeseele P, Kus JV, Lefebvre B, Haldane D, Garceau R, German G, Zahariadis G, Hanley B. Increase in ST-11 serogroup W Neisseria meningitidis invasive meningococcal disease in Canada, 2016-2018. Can Commun Dis Rep. 2019 Jun 6;45(6):164-169. doi: 10.14745/ccdr. v45i06a04. PMID: 31285709; PMCID: PMC6587698
Martin I, Sawatzky P, Allen V, Lefebvre B, Hoang L, Naidu P, Minion J, Van Caeseele P, Haldane D, Gad RR, Zahariadis G, Corriveau A, German G, Tomas K, Mulvey MR. Multidrug-resistant and extensively drug-resistant Neisseria gonorrhoeae in Canada, 2012-2016. Can Commun Dis Rep. 2019 Feb 7;45(2-3):45-53. doi: 10.14745/ccdr. v45i23a01. PMID: 31015818; PMCID: PMC6461123.
Parra-Herran C, Cesari M, Djordjevic B, Grondin K, Kinloch M, Köbel M, Pirzada A, Plotkin A, Gilks CB. Canadian Consensus-based and Evidence-based Guidelines for Benign Endometrial Pathology Reporting in Biopsy Material. Int J Gynecol Pathol. 2019 Mar;38(2):119-127. doi: 10.1097/PGP.0000000000000481. PMID: 29369922.
Huang Y, Campbell E, Colbourne B, Power J, Randell E. User competency is still a major factor affecting analytical performance of glucose meters in patient service. Clin Biochem. 2019 Jan; 63:66-71. doi: 10.1016/j.clinbiochem.2018.11.008. Epub 2018 Nov 30. PMID: 30508517.
Huang Y, Tian Y, Likhodii S, Randell E. Baseline urinary KIM-1 concentration in detecting acute kidney injury should be interpreted with patient pre-existing nephropathy. Pract Lab Med. 2019 Mar 7;15: e00118. doi: 10.1016/ j. plabm. 2019. e00118. PMID: 30989103; PMCID: PMC6447747.
Li, S., Xu, Y., Randell, E. W., Han, F. Y., Zheng, H., Zou, L., & Xie, Y. G. 2019. MTHFR677T and 1298C Play Independent but Opposite Effects in Stroke-Additive Co-Effect of two Intragenic Alleles. Biomedical Journal of Scientific & Technical Research,17(1), 12563-12569.
Randell EW, Yenice S. Delta Checks in the clinical laboratory. Crit Rev Clin Lab Sci. 2019 Mar;56(2):75-97. doi: 10.1080/10408363.2018.1540536. Epub 2019 Jan 11. PMID: 30632840.
Zhai G, Pelletier JP, Liu M, Randell EW, Rahman P, Martel-Pelletier J. Serum lysophosphatidylcholines to phosphatidylcholines ratio is associated with symptomatic responders to symptomatic drugs in knee osteoarthritis patients. Arthritis Res Ther. 2019 Nov 6;21(1):224. doi: 10.1186/s13075-019-2006-8. PMID: 31694709; PMCID: PMC6836440.
Zhai G, Pelletier JP, Liu M, Aitken D, Randell E, Rahman P, Jones G, Martel-Pelletier J. Activation of The Phosphatidylcholine to Lysophosphatidylcholine Pathway Is Associated with Osteoarthritis Knee Cartilage Volume Loss Over Time. Sci Rep. 2019 Jul 4;9(1):9648. doi: 10.1038/s41598-019-46185-w. PMID: 31273319; PMCID: PMC6609700.