Dr. William R. Driedzic
Bachelors: B.Sc. York
Masters: M.Sc. Toronto
Doctoral: Ph.D. U.B.C.
Telephone: (709) 864-3282
E-mail: wdriedzic@mun.ca
List all publications
Research Interests:
My research interests focus on the impact of environmental challenge, especially low oxygen and temperature extremes, on metabolic pathways. Current activities include: cardiac adaptations to anoxia, glycerol as a protective agent against low temperature, and control of protein synthesis. Experiments are conducted with a range of animals and tissues and at different levels of organization ranging from isolated proteins to whole animal cardiovascular performance. Furthermore, studies are designed to exploit the unique properties of selected marine organisms to lend fundamental insights into human disease issues such as diabetes and myocardial ischemia.
Recent Publications:
Costa, I. A. S. F.; Driedzic, W.R.; Gamperl, A.K. (2013). Metabolic and cardiac responses of cunner (Tautogolabrus adspersus) to seasonal and acute changes in temperature. Physiological and Biochemical Zoology. 86 (2) 233-244. (Click here for Abstract)
Ditlecadet, D.; Driedzic, W.R. (2013). Glycerol-3-phosphatase and not lipid recycling is the primary pathway in the accumulation of high levels of glycerol in rainbow smelt (Osmerus mordax – cycling thru' lipids vs GPase. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology. 304 (4) R304-R312. (Click here for Abstract)
Driedzic, W.R.; Clow, K.A.; Short, C.E. (2013). Glucose uptake and metabolism by RBCs fromfish with different extracellular glucose levels. Journal of Experimental Biology. 216 (3) 437-446. (Click here for Abstract)
Treberg, J.R.; Stacey, J.E.; Driedzic, W.R. (2012). Vanadium accumulation in ascidian coelomic cells is associated with enhanced pentose phosphate pathway capacity but not overall aerobic or anaerobic metabolism. Comparative Biochemistry And Physiology B-biochemistry & Molecular Biology. 161 (4) 323-330. (Click here for Abstract)
Hall, J.R.; Short, C.E.; Rise, M.L.; Driedzic, W.R. (2012). Expression Analysis of Glycerol Synthesis-Related Liver Transcripts in Rainbow Smelt (Osmerus mordax) Exposed to a Controlled Decrease in Temperature. Physiological And Biochemical Zoology. 85 (1) 74-84. (Click here for Abstract)
Clow, K.A.; Driedzic, W.R. (2012). Glycerol uptake is by passive diffusion in heart but by facilitated transport in RBCs at high glycerol levels in cold acclimated rainbow smelt (Osmerus mordax). American Journal Of Physiology - Regulatory, Integrative And Comparative Physiology. 302 (8) R1012-R1021. (Click here for Abstract)
Lamarre, S.G.; Ditlecadet, D.; McKenzie, D.J.; Bonnaud, L.; Driedzic, W.R. (2012). Mechanisms of protein degradation in mantle muscle and proposed gill remodeling in starved Sepia officinalis. American Journal of Physiology-regulatory Integrative and Comparative Physiology. 303 (4) R427-R437. (Click here for Abstract)
Ditlecadet, D.; Short, C.E.; Driedzic, W.R. (2011). Glycerol loss to water exceeds glycerol catabolism via glycerol kinase in freeze resistant rainbow smelt (Osmerus mordax). American Journal Of Physiology- Regulatory, Integrative And Comparative Physiology. 300 (3) R674-R684. (Click here for Abstract)
Robinson, J.L.; Hall, J.R.; Charman, M.; Ewart, K.V.; Driedzic, W.R. (2011). Molecular Analysis, Tissue Profiles and Seasonal Patterns of Cytosolic and Mitochondrial GPDH in Freeze Resistant Rainbow Smelt (Osmerus mordax). Physiological And Biochemical Zoology. 84 (4) 363-376. (Click here for Abstract)
Gendron, R.L.; Armstrong, E.; Paradis, H.; Haines, L.; Desjardins, M.; Short, C.E.; Clow, K.A.; Driedzic, W.R. (2011). Osmotic pressure-adaptive responses in the eye tissues of rainbow smelt (Osmerus mordax). Molecular Vision. 17 ( 279-82) 2596-2604. (Click here for Abstract)
