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Dr. Hu Liu

Please note that Dr. Liu is not taking graduate students at this time.

Dr. Hu Liu

Professor
hliu@mun.ca
Phone: 709 777 6382
H3423

Professor Hu Liu did his postsecondary education in Beijing, China and obtained B.Sc. (Pharm) and M.Sc. (Pharmaceutical Chemistry) degrees from Beijing Medical University (now Peking University).

In 1987, he came to Canada to continue with his studies in chemistry and biochemistry.

Under the supervision of Professor Robert O. Ryan he obtained his Ph.D. degree in lipid and lipoprotein biochemistry from the University of Alberta, Edmonton, Alberta, Canada in 1993.

Subsequently, Dr. Liu did his post-doctoral research training under the guidance of Professor Raymond E. Counsell at Departments of Pharmacology and Medicinal Chemistry of the University of Michigan, Ann Arbor, MI, USA.

In 1994, he took a faculty position at the School of Pharmacy, Memorial University of Newfoundland, St. John’s, NL, Canada, where he is currently a full professor. He also holds cross-appointments at the same university in the Division of BioMedical Sciences of Faculty of Medicine and the Department of Biochemistry of Faculty of Science.

From 1999 to 2004 Professor Liu was the recipient of the Career Award in Health Sciences sponsored by Canadian Institutes of Health Research (CIHR) and the Health Research Foundation of Canada’s Research Based Pharmaceutical Companies (Rx&D-HRF).

In 2000, he was awarded with the AstraZeneca New Investigator Research Award by the Association of Faculties of Pharmacy of Canada.

He has served as an internal grants reviewer for the Pharmaceutical Sciences Committee of CIHR.

Professor Liu also holds an adjunct professorship sponsored by the Education Commission of Beijing Municipality to engage teaching and research activities at the School of Chemical Biology and Pharmaceutical Sciences of Capital Medical University, Beijing, China.

His research interests include development of drugs and drug delivery systems in the areas of cancer, cardiovascular diseases and inflammation.

 

Selected Publication:

 

Wu Xiao; Thomas M. Scott, Liping Feng, Zhongshui Yu, Lili Wang, Jeffrey A. Hughes, Hu Liu (2003). Acetylated Low-density Lipoprotein (AcLDL) Encapsulated Cholesteryl 1,3-Diiopanoate Glyceryl Ether (C2I) for the Detection of Atherosclerosis In Rabbits. Journal of Nuclear Medicine, 44, 770-773.

 

Zhili Kang, Thomas M. Scott, Carl A. Wesolowski, Liping Feng, Zheyu Wang, Lili Wang, Hu Liu (2003) Ex Vivo Evaluation of a Novel Polyiodinated Compound for Early Detection of Atherosclerosis. Radiation Research. 160, 460-466.

 

Zhao, M.; Liu, J.; Wang, C.; Wang, L.; Liu, H. and Peng, S. Synthesis and Biological Activity of Nitronyl Nitroxide Containing Peptides. Journal of Medicinal Chemistry; 2005; 48(13); 4285-4292.

 

Hu Liu. Targeted Radioimaging Probes (invited front cover feature article). Cath Lab Digest; 2005; 13(7); 1,6

 

Wei Yang, Gene R. Herzberg, Zhili Kang, Lili Wang, Desmond Robb, Edward Randell, John Smeda, Jieying Xiong, Mohamedtaki Kara, Hu Liu; Attenuation of ciclosporin-induced nephrotoxicity by dietary supplementation of seal oil in Sprague-Dawley rats. Journal of Pharmacy and Pharmacology, 2005, 57(11):1485-1492.

 

Guohui Cui, Lili Wang, Philip J. Davis, Mohameditaki Kara and Hu Liu. Preparation and physical characterization of a novel marine oil emulsion as a potential new formulation vehicle for lipid soluble drugs International Journal of Pharmaceutics. 2006; 325(1-2):180-5.

 

Zheyu Wang, Krista Butt, Lili Wang and Hu Liu. The Effect of Seal Oil on Paclitaxel Induced Cytotoxicity and Apoptosis in Breast Carcinoma MCF-7 and MDA-MB-231 Cell Lines. Nutrition and Cancer-An International Journal, 2007; 58(2): 230-238.

 

Yu Shu and Hu Liu. Reversal of P-Glycoprotein (P-gp)-Mediated Multidrug Resistance by Low Density Lipoprotein (LDL) in a Vinblastine Resistant Human Lymphoblastic Leukemia Cell Line. Biochemistry and Cell Biology, 2007, 85(5): 638-646.

 

Ming Zhao, Xin Jia, Chao Wang, Qin Li, Kexiang Zhou, Lili Wang, Hu Liu, Shiqi Peng. PAK: An Essential Motif for Forming β-Turn Structures and Exhibiting Thrombolytic Effect in P6A Peptide and Its Analogs, Biochemistry and Cell Biology. 2007; 85(6): 730-740.

 

Mei Yang, Guohui Cui, Ming Zhao, Chao Wang, Lili Wang, Hu Liu, Shiqi Peng. The effect of complexation of Cu (II) with P6A peptide and its analogs on their thrombolytic activities. International Journal of Pharmaceutics, 2008, 362 (10): 81-87.

 

Boyang Liu, Chunying Cui, Ming Zhao, Shiqi Peng, Lili Wang, Hu Liu, Guohui Cui. Synthesis and evaluation of anti-tumor activity of N4 fatty acyl-amino acid-derivatives of 1-β-arabinofuranosylcytosine. European Journal of Medicinal Chemistry, 2009, 44(9), 3596-3600.

 

Chunying Cui, Yunwei Zhang, Lili Wang, Hu Liu, Guohui Cui. Enhanced anticancer activity of glutamate prodrugs of all-trans retinoic acid. Journal of Pharmacy and Pharmacology, 2009, 61, 1353-1358.

 

Chunying Cui, Boyang Liu, Huiling Wang, Lili Wang, Hu Liu, Guohui Cui. Improved anticancer activities of self-assembled nanoparticles of Cytarabine prodrug derivatives in solid tumors. Nanomedicine: Nanotechnology, Biology and Medicine, submitted on April 26, 2010, Reference #JN201060.

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