specific to regions of
particular chromosomes are
to fluorescent markers and hybridized with a chromosome spread.
shows a computer-generated "false colour"
image, in which small
in fluorescence wavelength among probes are enhanced as distinct
colours. The combination of probes that hybridize to a particular
produces a unique pattern for each chromosome. This makes it
particularly easy to detect segmental deletions and translocations
& image © 2008 by Steven M.
Carr, after original by
Genetix, with permission