is an introduction to the chemistry and structure-function relationships of carbohydrates, lipids and proteins. It will examine the basic metabolism of carbohydrates and fats, with emphasis on the biochemical fluctuations that occur in human health and disease, and will include a brief introduction to molecular genetics. Entry into this course is restricted to students in the Bachelor of Science in Nursing (Collaborative) Program and those signed in by special permission. Prospective Bachelor of Science in Nursing (Collaborative) program students should consult with the Faculty of Nursing concerning admission to this course.

examines the substances humans put into their bodies and the impact the substances have on cellular physiology and metabolism. With a special emphasis on current trends, the course introduces the concept of foods and drugs, how they are metabolised by the body, the social and political implications of foods and drugs, how they can influence overall health, and the sometimes grey areas between foods and drugs.

introduces the concepts of the composition of foods, and how the processing of food affects sensory appeal, shelf life and nutrient composition. Common food and water-borne illnesses (risks and prevention) are covered in the course content. Students will also be introduced to food biotechnologies, including genetically modified organisms, nutraceuticals and the development of functional foods.

will cover the heritability of simple traits from phenotype to genotype; the discovery of DNA as the molecule of heredity; the structure and function of DNA; the elucidation of the genetic code; and the manipulation of DNA for recombinant DNA technology and biotechnology.

will cover the heritability of simple traits from phenotype to genotype; the discovery of DNA as the molecule of heredity; the structure and function of DNA; the manipulation of DNA for recombinant DNA technology and biotechnology; and briefly, pharmacogenetics. Biology students should normally take Biology 2250 in the Fall semester, and Biochemistry and Biochemistry (Nutrition) students should normally take BIOC 2200 in Winter semester.

(same as the former BIOC 2101) is an introduction to the major organic substances of living organisms, proteins, carbohydrates and lipids: their structure, analysis and biochemical function. Other topics include: enzymes; the biochemistry of membranes, including the plasma membrane and specialized intracellular membranes; and the biochemistry of selected differentiated cells.

(same as Human Kinetics 2600) gives an overview of human nutrition with an emphasis on topics of current interest. Students will gain an understanding of nutrition in the context of health maintenance across the life span. Topics covered will include nutrition during pregnancy, nutrition for infants, Canadian Recommended Nutrient Intakes / Dietary Reference Intakes, weight loss and weight gain, nutriceuticals and ergogenic aids.

develops robust basic biochemistry lab skills in the context of a biotechnology project; students purify and characterize a recombinantly expressed enzyme. Students learn skills including safety, pipetting, buffer calculations, making solutions, protein bioinformatics, techniques for protein enrichment, enzyme kinetics measurements and calculations, graphing data, keeping a lab book, teamwork, critical analysis and presentation of their work in several formats. Students may co-author a scientific publication based on their results.

(same as Biology 3052) is the study of the microbiology of water and food with regard to the beneficial and detrimental roles of microorganisms on interaction with these systems. Emphasis will be on the microbiology of food, fermentations, food spoilage and food borne vectors of human disease.

examines topics such as: types of intermolecular forces in biomolecules; the folding of biomolecules and the role of water; pH, buffers, and ionisation of biomolecules; thermodynamics: equilibria, coupled reactions, transport across membranes and redox reactions; and ligand binding. Other topics will include: size and shape of biomolecules; isotopes in biochemistry; and, spectroscopy of biomolecules.

examines the catabolism of carbohydrates, lipids and amino acids. Other topics will be: mitochondria, chloroplasts and ATP synthesis; biosynthesis of carbohydrates and lipids; metabolic specialization of differentiated cells and tissues; and, integration of metabolism.

examines the structure, function and biochemistry of DNA and RNA and the biochemical processes in the flow of information from the gene to protein. These will include: DNA replication, recombination and repair processes; transcription of RNA and RNA splicing; and protein synthesis. The regulation of gene expression will also be covered at an introductory level. The course will also include an introduction to cloning methodology.

focuses on the molecular biochemistry of intracellular regulation, including advances in topics such as signal transduction, apoptosis and cancer. Other topics will include protein processing and sorting, cyclins, G-protein structure, function and regulation, cell adhesion molecules and the structure of the extracellular matrix.

- inactive course.

- inactive course.

is the cornerstone course for the study of nutrition. The sources, uptake and physiologic roles of essential nutrients will be discussed in the context of growth, maintenance, reproduction and overall health in humans.

examines the catabolism of carbohydrates, lipids and amino acids. Other topics will be: mitochondria, chloroplasts and ATP synthesis; biosynthesis of carbohydrates and lipids; metabolic specialization of differentiated cells and tissues; and, integration of metabolism.

examines the structure, function and biochemistry of DNA and RNA and the biochemical processes in the flow of information from the gene to protein. These will include: DNA replication, recombination and repair processes; transcription of RNA and RNA splicing; and protein synthesis. The regulation of gene expression will also be covered at an introductory level. The course will also include an introduction to cloning methodology.

examines the following topics: water structure and the role of water in chemical reactions and mechanical properties of foods; chemistry and physical properties of carbohydrates, proteins and lipids; food dispersions; pigments and natural colorants; food flavour; enzyme properties and applications; vitamins and minerals; chemistry of enzymic and non-enzymic browning; characteristics of: muscle tissue, milk, eggs, bread and edible plant tissue; food additives; and, chemical changes in foods during processing.

deals with the specific roles of nutrients in sport and exercise, and the application of nutrition to sport and exercise.

teaches advanced biochemical lab and critical thinking skills with a focus on metabolism and nutrition-related biochemistry. Topics may include animal diet formulation, tissue culture, immunoblots, metabolic flux assays, metabolic regulation, nutrient metabolism, metabolomics and metabolic energetics. Students develop their quantitative reasoning, teamwork, and written and oral communication skills. Students may have opportunities to tour lab facilities and to co-author a scientific publication based on their results.

develops biochemical lab and critical thinking skills through a molecular biology focused project. Topics may include restriction digestion, PCR amplification-based techniques, recombinant DNA and plasmid construction, gene expression systems, nucleic acid bioinformatics, and application of high through-put methods in molecular biology. Students develop their quantitative reasoning, teamwork and communication skills (written and oral). Students may have the opportunity to coauthor a peer-reviewed scientific publication based on their results.

examines metabolic regulation at the cellular and multicellular level. Topics will include: control theory; hormones: their biosynthesis and mechanism of action; signal transduction; and, endocrine coordination of metabolic processes. Principles will be illustrated by the use of case studies from the medical and veterinary literature.

will review the history of protein research and the general properties of proteins and include other topics such as: strategy and methods for purification; chemical structure, properties, modification and determination of the protein amino acids; sequencing strategy, chain cleavage methods and end group analysis; folding of the protein main chain and techniques to determine structure; and, the relationship between structure and function: protein filaments, motors and regulators. It will also cover disease-related proteins and other examples from the current literature.

is a seminar course in which faculty and students will discuss topics of current interest in the biochemical literature. Students will be responsible for reading and critically assessing recent literature.

is a detailed and up-to-date treatment of the mechanisms of genetic regulation found in bacterial cells. The course will develop topics based on the evidence of bacterial genetics and modern molecular biological experiments. Topics may include: theory of mutations, RNA transcription, positive and negative regulation of transcription; regulation of protein synthesis; control of DNA replication; bacterial operons and regulons; developmental molecular biology in bacterial systems; and evolution and molecular biology of organelles.

details the cellular and molecular aspects of eukaryotic gene regulation and development. Topics to be covered will include the DNA content and organization of eukaryotes, mechanisms controlling the expression of eukaryotic genetic information at the transcriptional and post-transcriptional levels, and the methodologies used to define these mechanisms. Detailed consideration will be given to the cell-surface events which regulate nuclear gene expression and cell lineage specification. Developmental mechanisms operating in a number of model systems will be discussed.

(same as Biology 4200 and Pharmacy 3006 and the former Pharmacy 4105) is an introduction to the cells and organs of the innate and adaptive immune systems. The molecular and cellular basis of allergy, autoimmunity, vaccination and cancer immunology will also be discussed.

examines topics such as: respiration and electron transport; the functional organization of energy transducing membranes; the structure and function of flavoenzymes, cytochromes, iron-sulfur proteins and quinones; enzyme reduction of oxygen; and, free radicals in biological systems.

examines the structure of model and biological membranes, the molecular interactions between membrane components and the effects of these interactions on the biophysical and functional properties of membranes. Other topics will include the structure-function of specialized membranous systems, such as lipoprotein, lung surfactant, and lipid rafts; membrane lipid composition in biochemical adaptation and function; and the role of membrane proteins in intracellular trafficking, receptor function, enzymatic activity and membrane-related diseases.

examines the proteome and the genome. This course is designed to familiarize students with current methodology employed in the analyses of the complements of proteins and genes resident in eukaryotic cells. Emphasis will be placed on techniques that facilitate the simultaneous functional analyses of large numbers of proteins or genes. A variety of techniques, used in the study of expression and functional proteomics, will be described, including 2D PAGE, tagged proteins, fluorophores, mass spectrometry and protein microarrays. Techniques used in the study of gene expression and functional genomics will also be described, including the use of reporter gene constructs, analysis of protein-DNA interactions, expressions of cloned genes and several experimental approaches used to define the eukaryotic transcriptome.

introduces students to the primary literature of metabolism. It teaches them to critique, both orally and in writing, current research papers. By means of guest lecturers and field trips it introduces students to biochemical activities outside of the home department.

is designed to provide current knowledge about advances and controversies in lipid and lipoprotein metabolism in the context of health and disease. Topics to be covered include advanced knowledge about lipid and lipoprotein synthesis and regulation, reverse cholesterol transport, plus lipid and lipoprotein utilization to regulate cellular and physiological functions. The covered topics will be related to areas such as reproductive biology, atherosclerosis, AIDS, Alzheimer’s, and cancer.

will explore the molecular biology of the bacteria that inhabit or invade human bodies, how these bacteria get established in humans, the biochemical mechanisms by which some bacterial pathogens can damage the host, and the contest for essential nutrients (e.g. iron) between bacteria and host.

will be given for senior undergraduates, and will cover a range of topics in specialized fields in Biochemistry. They may be taught by visiting specialists when available.

is designed to familiarize students with emerging discoveries in the area of diet-gene interaction and to further their understanding of the relationships between the genome and diet as well as the potential to design personalized diets for better health. Students will develop an appreciation for the role of nutrients in the prevention and/or development of disease.

will be given for senior undergraduates, and will cover a range of topics in specialized fields in Nutrition. They may be taught by visiting specialists when available.

is a course in which current controversies and trends in human nutrition are presented and discussed using the scientific literature.

is a course which addresses the scientific basis for nutritional intervention in chronic human disease.

is a seminar course in which faculty and students will discuss concepts and methods used in the study of nutrition. Students will be responsible for reading and critically assessing recent literature.

is the independent study of a problem in Biochemistry and is obligatory for Honours students in Biochemistry and Biochemistry(Nutrition). Faculty advisors will guide the subject of study which must be approved by the Head of the Department or delegate. The written dissertation shall be submitted by the end of the tenth week of the second semester. At the end of that semester the student will give an oral presentation and answer questions on their study.