Human v Chimp
              Chromosome 2

Robertsonian fusion of ape chromosomes in Homo

    Humans have 2n=46 chromosomes, as compared with 2n=48 in all of our other closest relatives, the Great Apes (Chimpanzee, Gorillas, and Orangutans). Whereas Chromosome 2 is a single, large sub-metacentric in humans, the other apes have two smaller, acrocentric chromosomes. Comparison of banding patterns allows these chromosomes to be aligned, and shows that during human evolution the ancestral chromosomes have undergone an end-to-end Robertsonian fusion to form a single larger chromosome. The gene contents of chimp and human chromosomes are substantially identical [note that the bands are conserved]. Molecular inspection of the area in the human 2q1.2~1.4 region shows telomere-like DNA sequences from the chimp chromosomes, as predicted.

Figure & text material ©2016 by Steven M. Carr