Drift &Fixation of rare alleles with strong selective advantage in finite populations
(N = 100, f(B0) = 0.005, W0 = W1 = 0.9, W2 = 1.0)
From a singleinitial allele (f(B) =
1/200 = 0.005 in N = 100 @) [left
graph], almost all populations go to f(B) = 0
within 20 generations, despite the selective advantage of
the BB genotype. Five populations reach f(B)
= 1 within 150 generations. Where the same
conditions apply to the A allele [right-hand
graph], Compare the trajectories and range of these stochastic
results with the deterministic expectation
[black curve].
Text material © 2021 by Steven M. Carr