NS 03-02smc

Basic Concepts of Coalescence: the MRCA

The array shows a population of haploid individuals that has a constant size of N=10 for 15 generations. Each horizontal row represents a generation; time proceeds upward.  Vertical lines in the graph connect parent-to-offspring descent. The coalescent ancestry of the two individuals sampled randomly from the Present generation is highlighted in red. Tracing both individuals from the Present (top row) downward (backwards in time), the Most Recent Common Ancestor (MRCA) of both individuals is found in the sixth generation backward from the present, when the two lineages coalesce on a single individual. The figure on the right show the resulting coalescence tree for the two individuals. The dots in the graph are called nodes. The two at the top are leaf nodes corresponding to the sampled individuals. The next older node down the tree corresponds to the MRCA of the two individuals.

HOMEWORK: The image from the textbook below contains at least one error: identify & explain the error(s).
03-02

Figures redrawn from © 2013 by Sinauer; Text material © 2022 by Steven M. Carr