Penetrance versus Expressivity
Egg
colour in Hawai'ian Oo'Aa birds
is controlled by a single locus, P, where P is dominant to p.
A pure-breeding line of purple-egg birds (PP) is crossed with a
pure-breeding line of white-egg birds (pp).
Because the offspring are all Pp heterozygotes, they are
therefore all expected to show a uniform, purple phenotype*. Two
variations from expectation are possible. If expressivity varies
[top right], the Pp genotype
will not be expressed uniformly: all eggs are purple, but some are more
or less purple than others. If penetrance varies
[left], the Pp genotype
sometimes does not manifest itself: some of the eggs are purple, like
the parental eggs, others are white. If expressivity and
penetrance
both vary [bottom right], there may be a continuous gradient of
phenotype
between white and purple eggs.
Note that lack of penetrance is an extreme from
of expressivity, in which the range of expression includes
non-expression.
*HOMEWORK: How would you distinguish this result from a cross Pp x pp, where the parents are
purple and white respectively, and half the offsping are purple Pp eggs and half are white pp eggs?