Deoxyribose vs
          Ribose Sugar

Deoxyribose versus Ribose sugars

    Ribose is a single-ring pentose [5-Carbon] sugar. The numbering of the carbon atoms runs clockwise, following IUPAC chemistry rules. The distinction between the two is the absence of the hydroxyl (-OH) group on the 2’ carbon in the deoxy-ribose sugar in DNA, as compared with the ribose sugar in RNA. The bulk of the extra Oxygen molecule in Ribose prevents it from forming stable double-helices.


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