
Bacteriophages ("Phages")
Bacteriophages ("bacteria
eaters") are viruses that attack bacteria. The name is commonly shortened to "phage". As seen in the electron micrograph,
phage comprise a "head" and "tail". The round "head"
contains DNA surrounded by a protein coat. Phages
attach to the outer membrane of bacteria by means of the thin
"tail", and inject DNA into the bacteria. The
phage multiply using the bacteria's gene system, which
eventually fill and rupture the bacteria, which releases more
phage. This has been likened to a tank that enters an auto
factory through the loading dock. The tank re-programs the
assembly line to make more tanks, which eventually crash
through the walls of the factory.
Early biochemical and genetic studies of
phage are the foundations of modern molecular biology.