Lysis & plaque formation by T1 bacteriophage on E. coli

The petri dish is covered by a uniform light grey lawn of E. coli bacteria. Addition of a small number of T1 bacteriophage allows each to infect a single bacterium, where it uses the cell's DNA to reproduce more of itself, eventually causing lysis and release of more phage particles. Infection and lysis clears a small plaque in the bacterial lawn, which appear here as dark grey circles.

All text material ©2017 by Steven M. Carr