In a population inbred to the extent

**f(AB) = 2pq(1-F)**

Rearranging to extract **F**:

**
(2pq)(1-F) = H _{obs}**

**2pq - (2pq)(F) = H _{obs}**

**
- (2pq)(F) = H _{obs} - 2pq**

**
F
= (H _{obs} - 2pq)/(-
2pq)**

**
F
= (2pq - H _{obs}) / (2pq)**

and since **2pq = ****H _{exp}**

**F
= (H _{exp}
- H_{obs}) / H_{exp}**

Text material © 2007 by Steven M. Carr