Dr. Mani Larijani - November 28

Taking the long way to solving the structure of a cancer-causing protein: an adventure in the 5th dimension

I will present five recent publications from my lab on our pioneering of a new methodology for solving protein structures. Instead of solving the 3-dimensional structure of proteins, our approach simultaneously resolves the prevalence of individual 3D states with respect to the 4th dimension (time), and a 5th dimension (function). I will also provide evidence for why this methodology allows for development of superior cancer therapeutics.



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