GENESIS Group Inc.
GENESIS Group Inc. is privately owned by Memorial and governed by a board of directors representing industry, academia, and government. It is here to serve the whole university community and to facilitate the linkage to business and community.
Genesis Research, as its primary goal, identifies and commercializes promising technologies arising from research at the university.
Areas of expertise include Biotechnology and Medicine, Physical Sciences and Engineering and Information Technology and Communications. In addition to its central role of transferring technology to the private sector, the research group assists the province's small and medium-size businesses to access the vast physical and human resources of the university. Genesis Research focuses on new technologies, processes, services and products that enhance, improve and/or diversify an existing industry's capability. In some instances it may create a new enterprise, which does not compete with the existing private sector.
Genesis Group Technologies
Liposomal Encapsulation of Biological Materials For Use In Aquaculture
Dr. Kevin Keough, Biochemistry Department, Memorial University
Mortality associated with bacterial disease is a major problem in aquaculture. Vaccination against bacterial disease has become an integral part of fish husbandry and several routes of administration of vaccines have been used with limited success, e.g., intraperitoneal injection, direct immersion, spraying onto the fish, and oral administration.
MUN researchers have developed an economic and practical delivery system for biological materials for use in aquaculture. Entrapment of antigen into multilanellar vesicles (liposomes), has been demonstrated by MUN researchers to enhance immune responses to the associated antigen. The use of liposomes to encapsulate antigens can also adjuvant activity and potentially increase immune responses to antigens delivered via any route. The liposomal delivery system technology can be designed to package and deliver vaccines, antibodies, vitamins and minerals, viruses and any other components requiring packaging. This technology could improve fish quality and quantity by reducing fish disease in fish husbandry.
This technology has been secured by an industrial partner under an option agreement.
Radioimaging Probes for the Early Detection of Atherosclerosis
Investigator:Dr. Hu Liu, School of Pharmacy, Memorial University
To date, the methods for detecting atherosclerotic plaques have been quite invasive and expensive. The detection method is usually used after the patient shows signs and symptoms of cardiovascular disease; by the time plaques are detected using traditional methods, there has already been significant build-up in the arteries. Dr. Liu has developed a method for the early detection of plaques that is simpler and less invasive than current techniques, enabling clinicians to perform broad-based population screens for atherosclerosis.
The invention involves the use of a novel chemical compound encapsulated into an acetylated LDL. The compound is administered via injection into the blood stream. The probe then travels to the site of atherosclerotic plaques and provides lesion specific delivery of the drug. The plaques can then be detected by g-scintigraphic imaging or computed tomography scanning (CT).
The radioimaging probes have a major implication for the early detection of atherosclerosis. Statistics show that there was 1,291,000 diagnostic cardiac catherizations performed in U.S. hospitals in 1998 and another 472,000 completed on outpatient clients. The cost of these procedures was $12,450 each on average for a total of US $21.9 billion.
Genesis Group Inc. is open to negotiations with relevant industrial partners who would be willing to undergo the following: licensing arrangement, joint venture, or option agreement. The patenting process for this technology has been initiated.
Permanent Magnet Hysteresis Reluctance Motor Investigator
Dr. Aziz Rahman, Faculty of Engineering and Applied Science, Memorial University
This hysteresis permanent magnet motor is an improved AC motor. It combines the best attributes of the modern permanent magnet, reluctance and hysteresis motors in one hybrid, resulting in high efficiency, high power factor and high performance in a synchronous mode of operation. Furthermore, it is simple and robust. This hysteresis-reluctance-permanent magnet motor has wide potential applications in AC drives requiring precision speed operation with built-in high starting, synchronising and pull-out torques.
The unique feature of the motor is embodied in its rotor design, while the stator is polyphase and a standard construction. The rotor has a cylindrical annular hysteresis ring with inside-cut slots for NdBFe magnets. The airgap is small and absolutely smooth so that the motor is very quiet. Performance is equivalent to a polyphase brushes synchronous motor; providing efficient, robust and economical operation. Its synchronous speed shows no variation due to fluctuations of voltage, frequency or load.
This motor is most suited for inside-out operations - e.g., drive motors for high-speed laboratory, commercial and industrial centrifuges, and spindle drives in paper and textile mills. Also, in miniature scale, it is suitable for high-speed computer disk drives, and gyros in aircraft and ship navigation systems. The closest technical competitor to this equipment in use today are PM motors in computer disk drives. This motor design has the potential to occupy at least 20 per cent of the line frequency ,start synchronous motor market, and 10 per cent of the variable frequency synchronous drive business.
The business side requires a partnership, details of which are open at this time, pending expressions of interest from capable companies. The partner should be able to define real commercial potentials for the moto; and ultimately provide for the facilities to manufacture the motors in commercial quantities.