Dr. Matthew Rise
Bachelors: B.Sc. Whitworth College
Masters: M.Sc. Boston College
Doctoral: Ph.D. University of Victoria
Telephone: (709) 864-7478
E-mail: mrise@mun.ca
List all publications
Research Interests:
My trainees and I develop and use genomic resources (e.g. DNA microarrays, SSH libraries for targeted gene discovery, and EST databases) in studies related to fish health. DNA microarrays are important tools in this work, as they allow a researcher to analyze relative expression levels of thousands of genes simultaneously. In my laboratory, experiments involving functional genomics techniques are used to identify and study the key genes involved in biological processes such as reproduction, development, growth, and responses to pathogens and environmental stressors (e.g. heat stress, pollutants). Some of the functional genomics techniques that we utilize include DNA microarray hybridizations, quantitative reverse transcription - polymerase chain reaction (QPCR), and SSH library construction and characterization.
Recent Publications:
Booman, M.; Borza, T.; Hori, T.S.; Feng, C.Y.; Higgins, B.; Culf, A.; Leger, D.; Chute, I.; Hall, J.R.; Belkaid, A.; Rise, M.; Gamperl, A.K.; Hubert, S.; Kimball, J.; Ouelette, R.; Johnson, S.C.; Bowman, S.; Rise,M.L. (2011). Development and experimental validation of a 20K Atlantic cod (Gadus morhua) oligonucleotide microarray based on a collection of over 150,000 ESTs. Marine Biotechnology. [This publication is currently 'In Press']
Bowman,S.; Hubert, S.; Higgins, B.; Stone, C.; Kimball, J.; Borza, T.; Bussey, J.T.; Simpson, G.; Hall, J.R.; Hori, T.S.; Feng, C.Y.; Gamperl, A.K.; Booman, M.; Rise, M.; Symonds, J.; Johnson, S.C.; Rise, M.L. (2011). An integrated approach to gene discovery and marker development in Atlantic cod (Gadus morhua). Marine Biotechnology. [This publication is currently 'In Press']
Rise, M.L.; Hall, J.R.; Rise, M.; Hori, T.S.; Browne, M.J.; Gamperl, A.K.; Hubert, S.; Kimball, J.; Bowman, S; Johnson, S.C. (2010). Impact of asymptomatic nodavirus carrier state and intraperitoneal viral mimic injection on brain transcript expression in Atlantic cod (Gadus morhua). Physiological Genomics. 42 (2) 266-280. (Click here for Abstract)
Hori, T.S.; Gamperl, A.K.; Afonso, L.O.B.; Johnson, S.C.; Hubert, S.; Kimball, J.; Bowman, S.; Rise, M.L. (2010). Heat-shock responsive genes identified and validated in Atlantic cod (Gadus morhua) liver, head kidney and skeletal muscle using genomic techniques. Bmc Genomics. 11 (72) (Click here for Abstract)
Callahan, A.G.; Deibel, D.; McKenzie, C.H.; Hall, J.R.; Rise, M.L. (2010). Survey of harbours in Newfoundland for indigenous and non-indigenous ascidians and an analysis of their cytochrome c oxidase I gene sequences. Aquatic Invasions. 5 31-39.
Lewis, J.M.; Hori, T.S.; Rise, M.L.; Walsh, P.J.; Currie, S. (2010). Transcriptome responses to heat stress in the nucleated red blood cells of the rainbow trout (Oncorhynchus mykiss). Physiological Genomics. 42 (3) 361-373. (Click here for Abstract)
Borza, T.; Stone, C.; Rise, M.L.; Bowman, S.; Johnson, S.C. (2010). Atlantic cod (Gadus morhua) CC chemokines: Diversity and expression analysis. Developmental And Comparative Immunology. 34 (8) 904-913. (Click here for Abstract)
Feng, C.Y.; Rise, M.L. (2010). Characterization and expression analyses of anti-apoptotic Bcl-2-like genes NIZ-13, Mcl-1, Bcl-X1, and Bcl-X2 in Atlantic cod (Gadus morhua). Molecular Immunology. 47 (4) 763-784. (Click here for Abstract)
Browne, M.J.; Feng, C.Y.; Booth, V.; Rise, M.L. (2010). Discovery and expression analyses of two novel, paralogous antimicrobial peptide-coding transcripts from Atlantic cod (Gadus morhua). Developmental And Comparative Immunology. [This publication is currently 'In Press']
Feng, C.Y.; Johnson, S.C.; Hori, T.S.; Rise, M.; Hall, J.R.; Gamperl, A.K.; Hubert, S.; Kimball, J.; Bowman, S.; Rise, M.L. (2009). Identification and analysis of differentially expressed genes in immune tissues of Atlantic cod stimulated with formalin-killed, atypical Aeromonas salmonicida. Physiological Genomics. 37 (3) 149-163. (Click here for Abstract)