Dr. Matthew Rise
Bachelors: B.Sc. Whitworth College
Masters: M.Sc. Boston College
Doctoral: Ph.D. University of Victoria
Telephone: (709) 864-7478
E-mail: mrise@mun.ca
List all publications
Research Interests:
My trainees and I develop and use genomic resources (e.g. DNA microarrays, SSH libraries for targeted gene discovery, and EST databases) in studies related to fish health. DNA microarrays are important tools in this work, as they allow a researcher to analyze relative expression levels of thousands of genes simultaneously. In my laboratory, experiments involving functional genomics techniques are used to identify and study the key genes involved in biological processes such as reproduction, development, growth, and responses to pathogens and environmental stressors (e.g. heat stress, pollutants). Some of the functional genomics techniques that we utilize include DNA microarray hybridizations, quantitative reverse transcription - polymerase chain reaction (QPCR), and SSH library construction and characterization.
Recent Publications:
Hall, J.R.; Short, C.E.; Rise, M.L.; Driedzic, W.R. (2012). Expression Analysis of Glycerol Synthesis-Related Liver Transcripts in Rainbow Smelt (Osmerus mordax) Exposed to a Controlled Decrease in Temperature. Physiological And Biochemical Zoology. 85 (1) 74-84. (Click here for Abstract)
Hori, T.S.; Rise, M.L.; Johnson, S.C.; Afonso, L.O.B.; Gamperl, A.K. (2012). The mRNA expression of cortisol axis related genes differs in Atlantic cod (Gadus morhua) categorized as high or low responders. General and Comparative Endocrinology. 175 (2) 311-320. (Click here for Abstract)
Hori, T.S.; Gamperl, A.K.; Booman, M.; Nash, G.W.; Rise, M.L. (2012). A moderate increase in ambient temperature modulates the Atlantic cod (Gadus morhua) spleen transcriptome response to intraperitoneal viral mimic injection. BMC Genomics. 13 (431) (Click here for Abstract)
Hori, T.S.; Gamperl, A.K.; Booman, M.; Nash, G.; Johnson, S.C.; Afonso, L.O.B.; Rise, M.L. (2012). Stress physiology and immune-relevant gene expression of Atlantic cod Gadus morhua subjected to elevated temperatures. Genome. 55 (10) 715-715.
Rise, M.L.; Hall, J.R.; Alcock, B.P.; Hori, T.S. (2012). Dynamic expression profiles of virus-responsive and putative antimicrobial "peptide-encoding transcripts during Atlantic cod (Gadus morhua) embryonic and. early larval development. Gene. 509 (2) 232-246. (Click here for Abstract)
Booman, M.; Rise, M.L. (2012). Genomic tools for understanding the molecular basis of production-relevant traits in finfish. Aquaculture Biotechnology. (Fletcher, G.L.; Rise, M.L, Eds.) 379p. (Click here for Abstract)
Booman, M.; Borza, T.; Hori, T.S.; Feng, C.Y.; Higgins, B.; Culf, A.; Leger, D.; Chute, I.; Hall, J.R.; Belkaid, A.; Rise, M.; Gamperl, A.K.; Hubert, S.; Kimball, J.; Ouelette, R.; Johnson, S.C.; Bowman, S.; Rise,M.L. (2011). Development and experimental validation of a 20K Atlantic cod (Gadus morhua) oligonucleotide microarray based on a collection of over 150,000 ESTs. Marine Biotechnology. 13 733-750.2.
Bowman,S.; Hubert, S.; Higgins, B.; Stone, C.; Kimball, J.; Borza, T.; Bussey, J.T.; Simpson, G.; Hall, J.R.; Hori, T.S.; Feng, C.Y.; Gamperl, A.K.; Booman, M.; Rise, M.; Symonds, J.; Johnson, S.C.; Rise, M.L. (2011). An integrated approach to gene discovery and marker development in Atlantic cod (Gadus morhua). Marine Biotechnology. 13 242-255. (Click here for Abstract)
Browne, M.J.; Feng, C.Y.; Booth, V.; Rise, M.L. (2011). Characterization and expression studies of Gaduscidin-1 and Gaduscidin-2; paralogous antimicrobial peptide-like transcripts from Atlantic cod (Gadus morhua). Developmental And Comparative Immunology. 53 (3) 399-408. (Click here for Abstract)
Feng, C.Y.; Rise, M.L. (2011). Identification and molecular cloning of Atlantic cod (Gadus morhua) activating transcription factor 3 (ATF3) transcript and its induction in spleen following intraperitoneal polyriboinosinic polyribocytidylic acid injection. Fish & Shellfish Immunology. 31 (3) 475-481. (Click here for Abstract)
