iGen3 05-10

7mG capping of hnRNA in eukaryotes

The 7-methyl-guanosine nucleotide is added to the tri-phosphorylated end of the hnRNA molecule. Other terminal bases are also methylated with -CH3 groups: methylation is a standard method by which cells mark particular nucleotides for special treatment.

Figure © 2010 PJ Russell, iGenetics 3rd ed.; all text material © 2014 by Steven M. Carr