Analysis of Strain #1 Arg- mutants

    Arg-Strain #1 is the only strain with a specific requirement for a specific amino acid, in this case arg. Therefore, arg must be the last amino acid synthesized in the pathway. The conversion of Y to arg is under control of the last enzyme in the pathway, C. Addition of either X or Y cannot produce growth, because although X can be converted to Y, in the absence of a functional enzyme CY cannot be converted to Z (arg).

All text & figure material © 2008 by Steven M. Carr