The Watson-Crick Model of DNA (1953)
Acid (DNA) is a double-stranded,
molecule. It consists of two sugar-phosphate
outside, held together by hydrogen bonds between pairs
on the inside. The bases are of four types (A, C,
T): pairing always occurs between A &
T, and C & G.
James Watson (1928 - ) and Francis
realized that these
rules meant that either strand contained all the information necessary to
new copy of the entire molecule, and that the order of bases
a "genetic code".
Watson and Crick shared the Nobel Prize in 1962 for their discovery, along with Maurice Wilkins (1916-2004), in whose lab Rosalind Franklin (1920-1958) had produced crystallographic evidence for a helical structure. Crick went on to do fundamental work in molecular biology and neurobiology. Watson become Director of the Cold Spring Harbor Laboratory, and headed up the Human Genome Project from the 1990s.