aquaticus colonies, Emerald Pool hot spring, Yellowstone
used in the polymerase chain reaction
were originally isolated from naturally-occuring bacteria (such as T. aquaticus) that grow in
near-boiling water of hot springs. The DNAPols
and other proteins in these "extremophile"
have adapted evolutionarily to be stable and functional at
high temperature. Temperature-resistant DNAPols are now
engineered to possess the particular properties required for optimal PCR.