Map of Yp11.3:
Zinc-Finger Protein, Y-linked (ZFY)
Sex-Recognition locus, Y-linked (SRY)

The ZFY and SRY loci map to the end of the short (p) arm of the Y chromosome. ZFY has protein domains characteristic of a DNA binding protein: its DNA sequence is widely used in tracing the inheritance of paternal lineages. SRY is critical in hormonal recognition that signals male development early in embryogenesis.

Figure ©2002 by Griffiths et al;. all text material ©2010 by Steven M. Carr