NS 08-14

Partial selective sweep of a new advantageous mutation in the absence of recombination

The novel SNP mutation is indicated by the red star: it necessarily arises in a single individual, with a potentially unique pattern of surrounding, genetically linked SNPs. Note in the example that the linked SNP to the left is shared with the the two chromosomes immediately above it, as an indication of common ancestry. The SNP to the right is unique.

Strong selection for the advantageous SNP may result in an increase in the prevalence of other SNP markers in the adjacent gene region (haplotype) without fixation. As previously, the haplotype SNP markers have no selective advantage in themselves.


Figures © 2013 by Sinauer; Text material © 2017 by Steven M. Carr