
Mendel's explanation of the
monohybrid
cross
Mendel
hypothesized that seed colour and other phenotypes are
controlled by alternative forms of an inherited "element"
(which
we now call a gene) in the parental
plants. Each
plant receives one factor
(now
called an allele)
from each
parent. The yellow plants have two copies of the "yellow"
factor (Y) and the
green plants two copies
of the "green"
factor (y). The F1 plants
receive one Y or one y factor from either
parent, and are
thus Yy. Since the plants are
yellow like
the YY parent, the Y factor can be said to dominate the y factor in determining
the
appearance of the seeds. That is, the heterozygous Yy combination
resembles the homozygous YY combination,
rather than the homozygous yy combination.
In gamete formation, the factors segregate (separate),
so that each
gamete carries only one or the other. One-half (1/2) of the
female
gametes are Y, 1/2
are y, and the same
is true for the male
gametes.
The probability
of
two independent events
occurring together is the product
of
their independent occurrence (the "and" rule). Then, the
probability
that any F2
plant
will receive a Y
from the
female and a Y from the male is (1/2)
x (1/2) =
1/4, and the probability of a y
from both parents is also (1/2) x (1/2) = 1/4.
The probability of two alternative events
occurring
together is the sum of
their
separate occurrence (the "or" rule). Then, there are two
ways of obtaining a Yy
plant: either Y
from the female and y
from the male, or y
from the female and Y
from the male: (1/2) x (1/2) + (1/2) x (1/2) = 1/2
Finally, the probability of a plant being
either YY or
Yy is 1/4 + 1/2 =
3/4, and the
probability of yy
remains 1/4.
The expected ratio of yellow ("Y-")
to green ("yy")
plants is 3/4 : 1/4
or 3:1, exactly as
observed.
Mendel showed that these ratios were
obtained for
seven separate traits
in peas, including seed colour and shape, pod shape, and
plant form.