Summary of hnRNA processing in eukaryotes

(a) RNA Polymerase initiates transcription of an hnRNA strand from the DNA template strand. (b) The 5' end of the hnRNA is capped with 7mG. (c) Transcription continues to the termination signal, after which (d) the trailing 3' end is removed. (e) The 3' end is polyadenylated. (f) The final hnRNA product is capped (to protect the 5' end) and tailed (to allow the 3' end to pass through the nuclear membrane.

Figure © 2002 Griffiths et al.; All text material © 2008 by Steven M. Carr