IG1_06_19

Post-transcriptional modification of tRNA bases

Primary tRNA molecules are transcribed from tDNA genes with the standard four bases. After assembly of mature tRNA molecules, specific bases are covalently modified so as to stabilize the tertiary structure.

Homework: In the structures above, identify which of the standard bases has been modified.

Figure © 2012 TA Brown, Introduction to Genetics (1st ed.); additional text © 2012 by Steven M. Carr