IG1_05_Fig22

Alternative splicing leads to different form of the same protein

The intron/exon-equivalent structure of the human dystrophin gene includes 35 exon-equivalents, of which 8 (those in green) are included or excluded in various combinations to produce an mRNA that is translated to make a tissue-specific form of the protein. The very large number of combinations means that the protein can be fine-tuned for tissue-specific functions.


Figure © 2012 TA Brown, Introduction to Genetics (1st ed.); additional text © 2012 by Steven M. Carr