Deamination mutagenesis
(a) Loss of an amine (NH2)
group changes C to U, which will pair with A.
(b) Methylation of
bases is one form of post-replication modification that marks
bases as newly-replicated. Methylated C bases (mC) can also be deaminated
to T, which will pair
with A.
Figure ©2000 by Griffiths et al. ; text ©2014 by Steven M. Carr