The genetic code for leucine (Leu)
can be either CUN or UUR. Consequently, either UUA or CUA,
as well as either UUG or CUG
code for Leu. That is, these first position
changes do
not change the amino acid, and the only exceptions to the rule that
first positions 'always' lead to amino acid substitutions in the
Universal Code.
Homework:
There are two other amino acids encoded by six codons each: explain why
they don't violate the rule