Substitution of Val for Glu in Sickle-Cell Anemia

Sickle-Cell Anemia is cause by a substitution of Glu to Val at the sixth amino acid position in the beta-chain hemoglobin protein.

Homework: What is the mutation in the sense strand of the DNA that causes this substitution?

Figure © 2004 by Griffiths et al.; text © 2014 by Steven M. Carr