Giemsa banding

    Giemsa staining of acid-denatured chromosomes reveals characteristic banding patterns that can be used to identify individual chromosomes. Giemsa is a protein stain: darkly-staining bands are described as heterochromatic, and correlate to genetically inactive chromosomal regions; lightly-staining areas are euchromatic and are associated with active regions. The G-banding pattern of human chromosomes links classical cytogenetics to genomics by assigning sets of genes to particular bands.

All text material ©2014 by Steven M. Carr