Fragile X chromosomeFragile X chromosome

Fragile X chromosome

    Fragile X chromosomes are characterized by satellite regions, visible at the bottom ends of the long arm (Xq2.6 region) of metaphase X chromosome, in the scanning electron micrograph and the Giemsa-stained photo (inset, upper right). The constrictions are due to a long series of CGG triplet repeats. Fragile X is associated with Martin-Bell Syndrome, the most common form of inherited predisposition to mental retardation.

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  Figure redrawn from Harrison et al. 1983 J Med Genet 20,280; text ©2014 by Steven M. Carr