
Fragile X chromosome
Fragile X chromosomes are
characterized by satellite regions, visible at the bottom
ends of the long arms of metaphase X chromosomes in the scanning electron micrograph
and the Giemsa-stained photo (inset, upper right). The
constrictions are due to a long series of CGG triplet repeats. Fragile X
is associated with Martin-Bell Syndrome, the most common
form of inherited predisposition to mental retardation.
[For further information, see http://www.fragilex.org/index.htm]