bromide is an intercalating dye
used as a nucleic acid stain. The main three-ring portion resembles a
purine-pyrimidine base pair, which is able to slip in between adjacent
co-planar base pairs (intercalation).
Under ultraviolet light, intercalated EtBr
with a strong pink-orange colour, and for this reason is used
extensively as a dye in DNA experiments.
Ethidium bromide is a very strong
mutagen, carcinogen, and teratogen that causes mutations,
developmental defects, respectively.
© 2009 by Steven M. Carr