Molecular & Developmental Biology (BIOL3530)

Department of Biology
Memorial University of Newfoundland

Professor:  Dr. Brian E. Staveley, Ph.D.

Laboratory Instructor (IA): Dr. Jennifer D. Slade, B.Sc. (Honours Biology), M.Sc. (Biology, MUN), Ph.D. (Biology, MUN)

Laboratory Demonstrator (TA): TBA


Due to this week's "Snowmageddon", the first lecture by Dr. Nicole LeDouarin will be assigned.
link: Nicole LeDouarin: Part 1 The Neural Crest in Vertebrate Development

Due to last Monday's "half snow day", the first lecture by Eric Wieschaus will be assigned.
link: Eric Wieschaus: Part 1 Patterning Development in the Embryo

Questions about these video lectures may be on the exams (mid-terms and final).

The first class and the introductory laboratory session are both on Friday January 6, 2017!

This is the homepage for Molecular & Developmental Biology (BIOL3530) for the Winter Semester of 2017.
Classes are on Monday, Wednesday and Friday at 11 am in the very comfortable room SN2067.
The laboratories are on most Friday's at 2 pm in TBA.
This revamped course is ideal for those interested in whole organism biology and in molecular and cellular biology.

Course Grades will be based upon:

15% Midterm Examination I (Friday February 3, 2017 in AA1049)
15% Midterm Examination II (Friday March 10, 2017 in AA1049)
40% Laboratory Research
    Laboratory Participation & Analysis (throughout semester 5%)
    Annotated Multiple Alignment(s) (5%)
    Introduction of paper/mini review (5%)
    Debate (TBA) (5%)
    Final Paper (20%)
30% Final Examination (Thursday April 13, 2017  at 9:00 AM in SN2067)

These pages contain the class note outlines for the BIOL3530: Molecular & Developmental Biology course.
Be certain that you take a copy of current notes with you to class.
Please note that to provide the most up-to-date and correct set of notes, the material may be edited as the class progresses.
In that spirit, please report any errors or broken links to me when found.

Molecular & Developmental Biology Subjects Areas:

BIOL3530: History and Basic Concepts
BIOL3530: Development of the Drosophila Body Plan
BIOL3530: Vertebrate  Development I: Life Cycles and Experimental Techniques
BIOL3530: Vertebrate  Development II: Axes and Germ Layers
BIOL3530: Vertebrate  Development III: Patterning the Early Nervous System and the Somites
BIOL3530: Development of Nematodes, Sea Urchins, and Ascidians
BIOL3530: Plant Development
BIOL3530: Morphogenesis: Change in Form in the Early Embryo
BIOL3530: Germ Cells , Fertilization and Sex
BIOL3530: Cell Differentiation and Stem Cells
BIOL3530: Organogenesis
BIOL3530: Development of the Nervous System
BIOL3530: Growth and Post-Embryonic Development, and Regeneration
BIOL3530: Evolution and Development
BIOL3530: Review (TBA)

BIOL3530: Molecular & Developmental Biology Laboratory Pages

Bonus Marks:
To encourage learning above and beyond the usual, a limited number of bonus marks will be given for innovation and enhanced learning opportunities.
1) Suggestions for mechanisms to earn bonus marks will be considered.
2) Students are encouraged to find and make suggestions to additional contributions to the "Molecular & Developmental Biology in the News" section.
These will be "peer-reviewed" periodically in the class or lab.

Bonus Mark Material
BIOL3530: Molecular & Developmental Biology in the News
BIOL3530: Molecular & Developmental Biology in Popular Culture

BIOL3530: Molecular & Developmental Biology in Everyday

Lectures on Drosophila Development (Supplemental) include:
BIOL3530: Molecular & Developmental Biology Video Links

PBS-Genetic Tool kit (How conserved are the developmental genes?)

Eric Wieschaus' Amazing talks about Drosophila embryonic development
Eric Wieschaus: Part 1 Patterning Development in the Embryo
Eric Wieschaus: Part 2 Stability of Morphogen Gradients & Movement of Molecules
Eric Wieschaus: Part 3 Evolution of Bicoid-based Patterning in the Diptera

Course Description:

BIOL3530: Molecular & Developmental Biology. A study of developmental systems with a focus on the underlying principles and molecular mechanisms involved in cellular differentiation, morphogenesis and growth. Three hours of lecture and three hours of laboratory per week.  Prerequisites: BIOL2060: Principles of Cell Biology.

Textbook (required):  Principles of Development by Lewis Wolpert, Cheryll Tickle & others, 5th edition
This is a revised and updated new edition of the best-selling and popular textbook on developmental biology written by one of the most influential developmental biologists of this century, Lewis Wolpert. Developmental biology is at the core of all biology. It deals with the processes by which the genes in the fertilized egg control cell behaviour in the embryo and so determine its pattern, form, and much of its behaviour. This book emphasizes the principles and key developments in order to provide an approach and style that will appeal to undergraduate students of all levels.

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