Course Description:
This course offers an advanced level of study into the development
of plants and animals with a concentration upon the most recent developments
underlying the principles of mechanisms involved in cell differentiation,
morphogenesis and growth. Major topics include an introduction to
the discipline of Developmental Biology, an exploration of developmental
processes in vertebrates, Drosophila and other organisms, and an examination
of the molecular and cellular mechanisms that drive development.
An emphasis will be placed upon the recent advancements in the identification
of the molecular basis of development.
Course lecture and laboratories will coincide with BIOL3530: Molecular
& Developmental Biology
Textbook (required): Principles
of Development by Lewis Wolpert & others, 3rd edition
This is a revised and updated new edition of the best-selling and popular
textbook on developmental biology written by one of the most influential
developmental biologists of this century, Lewis Wolpert. Developmental
biology is at the core of all biology. It deals with the processes by which
the genes in the fertilized egg control cell behaviour in the embryo and
so determine its pattern, form, and much of its behaviour. This book emphasizes
the principles and key developments in order to provide an approach and
style that will appeal to undergraduate students of all levels.
National Center for Biotechnology
Information
Web of Science
Flybase
The
Interactive Fly
European Bioinformatics Institute
Multiple sequence alignment:
Clustal W program produces biologically meaningful alignments: http://www.ebi.ac.uk/clustalw/.
Proteomic tool resources:
Computational Molecular Biology At NIH: http://molbio.info.nih.gov/molbio/analysis.html
ExPASy Proteomics Tools: http://us.expasy.org/tools/#proteome
Protein analysis:
InterPro Scan: http://www.ebi.ac.uk/InterProScan/
ProDom: http://protein.toulouse.inra.fr/prodom/current/html/home.php
Pfam: http://www.sanger.ac.uk/Software/Pfam/
email me at bestave@mun.ca