The Molecular Biology of Development (BIOL7530)

Department of Biology
Memorial University of Newfoundland
telephone: 737-4317

Professor:  Dr. Brian E. Staveley, Ph.D.

Laboratory Instructor (IA): Jennifer Slade, B.Sc. (Honours Biology), M.Sc. (Biology), Doctoral Candidate

Laboratory Demonstrator (TA): Colleen Connors, B.Sc. (Biology, minor in Math), M.Sc. (Biology), Doctoral Student

Laboratory Demonstrator (TA): Peter M'Angale B.Sc. (Zoology: Moi University, Kenya), M.Sc. (Biology, MUN), Doctoral Candidate


This is the homepage for The Molecular Biology of Development (BIOL7530) for the Winter Semester of 2013.
Classes are on Monday, Wednesday and Friday at 11 am in the very comfortable room SN2067.
The laboratories are on most Friday's at 2 pm in SN4098 & SN4117.
This revamped course is ideal for those interested in whole organism biology and in molecular cell biology.

Molecular & Developmental Biology Subjects Areas:

BIOL3530: History and Basic Concepts
BIOL3530: Development of the Drosophila Body Plan
BIOL3530: Vertebrate  Development I: Life Cycles and Experimental Techniques
BIOL3530: Vertebrate  Development II: Axes and Germ Layers
BIOL3530: Vertebrate  Development III: Patterning the Early Nervous System and the Somites
BIOL3530: Development of Nematodes, Sea Urchins, and Ascidians
BIOL3530: Plant Development
BIOL3530: Morphogenesis: Change in Form in the Early Embryo
BIOL3530: Germ Cells , Fertilization and Sex
BIOL3530: Cell Differentiation and Stem Cells
BIOL3530: Organogenesis
BIOL3530: Development of the Nervous System
BIOL3530: Growth and Post-Embryonic Development
BIOL3530: Regeneration
BIOL3530: Evolution and Development
BIOL3530: Review (TBA)

These pages contain the class note outlines for the BIOL3530: Molecular & Developmental Biology course.
Be certain that you take a copy of current notes with you to class.
Please note that to provide the most up-to-date and correct set of notes, the material may be edited as the class progresses.
In that spirit, please report any errors or broken links to me when found.

Out of Class Assignment:

Watch all three lectures by
Nobel Prize Molecular Developmental Biologist and Geneticist, Dr. Eric Wieschaus
Part 1: Patterning Development in the Embryo
Part 2: Stability of Morphogen Gradients & Movement of Molecules
Part 3: Evolution of Bicoid-based Patterning in the Diptera

Material for Testing on Midterms I & II and Final Examination

BIOL3530: Molecular & Developmental Biology Laboratory Pages

BIOL3530: Molecular & Developmental Biology Video Links

BIOL3530: Molecular & Developmental Biology in the News


Developmental Biology Assignment Information:

Course Grades will be based upon:

15% Midterm Examination I (February 8th, 2013)
15% Midterm Examination II (March 8th, 2013)
  5% Seminar Presentation (TBA)
30% Laboratory Research Paper (includes participation)
    Annotated Multiple Alignment(s) (Feb 15, 2013 -5%)
    Introduction of paper (TBA -5%)
    Final Paper (March 22, 2013 -20%)
35% Final Examination (TBA)

Course Description:

BIOL3530: Molecular & Developmental Biology. A study of developmental systems with a focus on the underlying principles and molecular mechanisms involved in cellular differentiation, morphogenesis and growth. Three hours of lecture and three hours of laboratory per week.  Prerequisites: BIOL2060: Principles of Cell Biology.
Course lecture and laboratories will coincide with BIOL3530: Molecular & Developmental Biology

Textbook (required):  Principles of Development by Lewis Wolpert, Cheryll Tickle & others, 4th edition
This is a revised and updated new edition of the best-selling and popular textbook on developmental biology written by one of the most influential developmental biologists of this century, Lewis Wolpert. Developmental biology is at the core of all biology. It deals with the processes by which the genes in the fertilized egg control cell behaviour in the embryo and so determine its pattern, form, and much of its behaviour. This book emphasizes the principles and key developments in order to provide an approach and style that will appeal to undergraduate students of all levels.

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